Ovarian adenocarcinoma of mesonephric type

Clear cell carcinoma of the ovary: evaluation of prognostic parameters based on a clinicopathological analysis of 100 cases

“…Improved survival was seen with a tubulocystic pattern in two studies, a ‘clear cell pattern’ (as opposed to a ‘tubular pattern’ or ‘glandular pattern’) in two studies, a papillary pattern in one study and a solid pattern comprising <50% of the tumour in the last study . Two additional studies showed a correlation between cell type and outcome; however, neither achieved statistical significance . In one, a predominance of clear cells was associated with improved survival, whereas in the other the converse was true .…”

“…Six of these studies demonstrated an association between architectural pattern and prognosis; [14][15][16][17][18][19] however, statistical significance was only achieved in two. 17,19 Improved survival was seen with a tubulocystic pattern in two studies, 15,17 a 'clear cell pattern' (as opposed to a 'tubular pattern' or 'glandular pattern') in two studies, 14,18 a papillary pattern in one study 16 and a solid pattern comprising <50% of the tumour in the last study. 19 Two additional studies showed a correlation between cell type and outcome; however, neither achieved statistical significance.…”

Clinical characteristics of clear cell carcinoma of the ovary

“…Only 3 of 27 patients (11.1%) responded to platinum-based che- 3,14 In contrast, several recent reports indicate that CCC is a histologic tumor type with a poor prognosis. 4,6,7,9,15,16 Many authors have discussed the prognosis of patients with CCC compared with that for patients with SAC; however, to our knowledge there had been no clear agreement in their findings.…”

Treatment Issues in Clear Cell Carcinoma of the Ovary: A Different Entity?

“…However, no clear agreement has been documented. Some reports published since 1970 have indicated no difference in outcome between patients with OCCC and their stage-matched, serous-subtype counterparts [7,28]. In addition, Kennedy et al [8] reported that stage I and II patients with OCCC had survival that was similar to that of patients with other EOCs, while stage III and IV OCCC patients had a more dismal outcome.…”