Outpatient Intravenous Antibiotic Therapy in Medicare Patients: Cost-Savings Analysis

Outpatient parenteral antimicrobial therapy (OPAT) for the treatment of osteomyelitis: evaluation of efficacy, tolerance and cost

“…As has been noted by others, cost savings are clear (34–36), but there is a need to take account of the possible costs of adverse effects and re‐hospitalization due to therapeutic failures.…”

The Community IntraVenous Antibiotic Study (CIVAS): a mixed-methods evaluation of patient preferences for and cost-effectiveness of different service models for delivering outpatient parenteral antimicrobial therapy

“…56 Of the remaining studies that considered acceptability in OPAT patients only, most involved multiple OPAT models (and did not differentiate between them in their findings), or did not specify the model(s) under study. In general, satisfaction with treatment was very high, 2,13,27,36,[67][68][69][70][71][72][73][74][75][76][77][78][79][80][81][82][83] including when patients had to have frequent attendance at hospital. 5,84 Commonly perceived advantages of OPAT included the ability to resume daily activities, 2,27,71,73 feelings of improved self-esteem or greater freedom and control, 67,71,73,85,86 and not having to remain in or attend hospital.…”

“…The initial review in 2013 identified 34 studies that examined patients' acceptability of OPAT, but, of these, 21 were quantitative surveys assessing satisfaction with the service and provided little information about patients' own perceptions of the benefits and disadvantages of OPAT. 5,12,13,15,25,27,36,41,67,68,70,73,[75][76][77][78][80][81][82]86,89 Only six interview-based studies were identified by the review. 35,37,79,85,88,99 The literature indicates that patients generally view OPAT very positively.…”

Safety and efficacy of home intravenous antimicrobial infusion therapy in older patients: a comparative study with younger patients

“…Some time later, papers on this subject were published in Spain (4–8). Besides proving safe and effective in a great variety of infectious diseases, such as acute pyelonephritis (9), community pneumonia (10) or cellulitis (11), several authors have reinforced the beneficial role of this approach by establishing its good cost‐benefit relation (12–14).…”