Outpatient Endometrial Sampling with the Pipelle Curette

Abstract

This study compares outpatient endometrial sampling using the Pipelle endometrial sampling curette with conventional dilation and curettage (D&C) in patients with abnormal uterine bleeding. Endometrial sampling with the Pipelle curette was performed in 172 and D&C in 97 women. No complications were encountered with either of these procedures. One hundred and seventy (98.8%) of the Pipelle aspirations attempted were successfully completed. Sufficient material for histological assessment was obtained in 154 (90.6%) of the women who underwent Pipelle endometrial sampling and in only 66 (68%) of those who underwent D&C (p < 0.0001). In postmenopausal women, adequate specimens were obtained in 74 of 88 (84.1 %) by Pipelle and in only 22 of 48 (45.8%) by D&C. In 45 cases the histologic diagnosis of the endometrium obtained by Pipelle sampling was compared with the one of endometrium obtained by D&C or hysterectomy performed shortly thereafter. The diagnosis was identical in 43 (95.5%) cases. Endometrial sampling with the Pipelle was well tolerated causing occasionally only slight discomfort.

Accuracy of outpatient endometrial biopsy in the diagnosis of endometrial cancer: a systematic quantitative review

“…A further 13 articles 50 -62 were identified through examination of the reference lists of the known primary publications and review articles. After independent review of the 52 manuscripts, 11 articles (10 English 16,36,38,39,43,46,50,52,57,62 , one French 35 ) were considered to be eligible for inclusion in the review (Fig. 1).…”

“…There were 1013 subjects in 13 diagnostic evaluations reported in 11 primary studies: 40 women in a single evaluation of the Accurette device 62 , 70 women in a single evaluation of the Gynoscann device 16 , 176 women in a single evaluation of the Novak curette 57 , 546 women in 16,35,50 and in three menopausal status was unclear 52,57 . Postmenopausal women represented 79% of the populations studied.…”

“…The assessment of outcome data shows that in only two (18%) of the studies were the outpatient test results reported to be masked from the pathologist interpreting the reference standard. Thus two studies 36,46 (18%) were level I, a further two studies 35,43 (18%) were level III and seven studies 16,38,39,50,52,57,62 (64%) were level IV in quality.…”

Accuracy of Hysteroscopy in the Diagnosis of Endometrial Cancer and Hyperplasia

“…This is because insufficient tissue samples are generally taken to mean absence of pathological findings. 45,46 We also excluded intrauterine polyps and fibroids as part of a sensitivity analysis to examine whether the presence of these focal lesions affected estimates of diagnostic accuracy.…”

Abklärung von perimenopausalen Blutungsstörungen

“…Insgesamt liegen die Spezifität und Sensitivität der D & C im Bereich der Pipelle, Vabra-und Novak-Curette [67,70,72,73,75,76] [75,[77][78][79][80][81][82].…”