Outdoor air pollution and cystic fibrosis

Brugha, Ruairı́; Edmondson, C.; Davies, Jane C.

doi:10.1016/j.prrv.2018.03.005

Cited by 21 publications

(16 citation statements)

References 47 publications

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“…But also, agricultural air pollutants contribute to human health problems (Aneja et al, 2009). Particulate air pollution was associated with an increased risk of pulmonary exacerbations in CF (Brugha et al, 2018), a decline in lung function (Goss et al, 2004) and can exert proinflammatory and immunomodulatory effects (Reinmuth-Selzle et al, 2017). Our findings may reflect that in urban as well as sparsely populated rural areas synergistic effects of more frequent Af acquisition and immunomodulatory effects of air pollution influence the CF patients Af outcome.…”

Section: Discussionmentioning

confidence: 66%

“…Our findings may reflect that in urban as well as sparsely populated rural areas synergistic effects of more frequent Af acquisition and immunomodulatory effects of air pollution influence the CF patients Af outcome. It is postulated that, pollution exposure early in life might associate with an increased risk of early infection to certain microbes (Brugha et al, 2018). Furthermore, the exposure to environmental factors might be even more harmful in children than in adults, because of behavioural and physiological factors (Goldizen et al, 2016).…”

Section: Discussionmentioning

confidence: 99%

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Urban Life as Risk Factor for Aspergillosis

Grehn

Eschenhagen

Temming

et al. 2020

Front. Cell. Infect. Microbiol.

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Aspergillus fumigatus (Af) frequently colonizes the airways of patients with cystic fibrosis (CF) and can cause severe diseases, such as allergic bronchopulmonary aspergillosis, Af bronchitis or even Af pneumonia. However, risk factors, including environmental factors, for acquiring Af in the respiratory tract of patients with CF are rarely studied and described. The aim of this study was to investigate whether urban or rural life could affect colonization with Af in the respiratory tract of patients with CF. Due to privacy policy, registry data are usually not linked to patients´home addresses. It is therefore very difficult to analyze the influence of the patient´s residential environment. This prospective questionnaire survey was carried out in 31 German CF centers in 2018. Only completed surveys, including a clearly assigned type of residential area were included. Statistical analysis was performed by chi-squared test and logistic regression models. A total of 1016 questionnaires were analyzed (Patients`age: 23 ± 13; 0-88 years; female gender: n=492; 48%). The majority of patients with CF live in large cities (n =314; 30.9%) or urban districts (n=461; 45.4%). Prevalence of 30.2% was found for Af, within the 12 months of investigation period. Af colonization was significantly associated with urban life (p=0.004). Urban live should be considered as possible new risk factor for colonization with Af in the respiratory tract of patients with CF. These new results may raise the awareness of the influence of environmental factors on patient outcomes and should be included in patient guidance and preventive measures.

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Section: Discussionmentioning

confidence: 66%

Section: Discussionmentioning

confidence: 99%

Urban Life as Risk Factor for Aspergillosis

Grehn

Eschenhagen

Temming

et al. 2020

Front. Cell. Infect. Microbiol.

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“…The World Health Organization has announced that 92% of the world's population live in zones with poor air quality [69]. Consequently, the lack of air quality has been identified as the reason for the increment of the premature death worldwide [69]. CO is one of the major air pollutants.…”

Section: Sensing Toward Carbon Monoxide (Co)mentioning

confidence: 99%

Low-Dimensional Nanostructures Based on Cobalt Oxide (Co3O4) in Chemical-Gas Sensing

Kumarage

Comini

2021

Chemosensors

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Highly sensitive, stable, low production costs, together with easy maintenance and portability, sensors are ever most demanded nowadays for monitoring and quantification of hazardous chemicals/gases in the environment. The utilization of one dimensional (1D) metal oxide nano structured chemical/gas sensors for environmental monitoring is vastly investigated because of their superior surface to volume ratio, stability, and low production costs, to provide information on the presence of chemical species. Several outstanding attempts have been pursued investigating 1D nano structures of Co3O4 over the past decades as an active material for chemical analytes detection owing to its superior catalytic effect together with its excellent stability. This article reviews the state-of-the-art of growth and characterization of Co3O4 1D nano structures and their functional characterization as chemical/gas sensors. Moreover, fundamental concepts and characteristic features, that enhance the key performances of chemical/gas sensors, are discussed. Finally, challenges and prospective for growth and fabrication of 1D Co3O4 chemical/gas sensors are discussed.

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“…Furthermore, benzene (C 6 H 6 ), toluene (C 7 H 8 ), and xylene (C 8 H 10 ) (BTX) gases are also generally present in pollutant air. It is considered that 92% of the world’s population lives in areas with poor air quality, which can cause premature death [ 2 ]. Pollution is the most important cause of premature death and illness worldwide, and it accounts for 16% of global death [ 3 ].…”

Section: Introduction: Overview Of the Oxide-based Gas Sensorsmentioning

confidence: 99%

State-of-the-Art Research on Chemiresistive Gas Sensors in Korea: Emphasis on the Achievements of the Research Labs of Professors Hyoun Woo Kim and Sang Sub Kim

Navale

Mirzaei

Majhi

et al. 2021

Sensors

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This review presents the results of cutting-edge research on chemiresistive gas sensors in Korea with a focus on the research activities of the laboratories of Professors Sang Sub Kim and Hyoun Woo Kim. The advances in the synthesis techniques and various strategies to enhance the gas-sensing performances of metal-oxide-, sulfide-, and polymer-based nanomaterials are described. In particular, the gas-sensing characteristics of different types of sensors reported in recent years, including core–shell, self-heated, irradiated, flexible, Si-based, glass, and metal–organic framework sensors, have been reviewed. The most crucial achievements include the optimization of shell thickness in core–shell gas sensors, decrease in applied voltage in self-heated gas sensors to less than 5 V, optimization of irradiation dose to achieve the highest response to gases, and the design of selective and highly flexible gas sensors-based WS2 nanosheets. The underlying sensing mechanisms are discussed in detail. In summary, this review provides an overview of the chemiresistive gas-sensing research activities led by the corresponding authors of this manuscript.

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Outdoor air pollution and cystic fibrosis

Cited by 21 publications

References 47 publications

Urban Life as Risk Factor for Aspergillosis

Urban Life as Risk Factor for Aspergillosis

Low-Dimensional Nanostructures Based on Cobalt Oxide (Co3O4) in Chemical-Gas Sensing

State-of-the-Art Research on Chemiresistive Gas Sensors in Korea: Emphasis on the Achievements of the Research Labs of Professors Hyoun Woo Kim and Sang Sub Kim

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