Outcomes of tympanostomy tube placement in children with Down syndrome—A retrospective review

Paulson, Lorien M.; Weaver, Tyler S.; MacArthur, Carol J.

doi:10.1016/j.ijporl.2013.10.062

Cited by 35 publications

(30 citation statements)

References 18 publications

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“…Thus, having a PET placed at an older age may be due to an unresolved, long-standing middle ear disease in children with DS. This finding of hearing loss in some children with DS, despite having patent PETs, has been reported in other studies (Austeng et al, 2013; Paulson et al, 2014; Manickam et al, 2016). Some DS cases had apparent sensorineural components by bone conduction at 2–4 kHz, but these could also represent “Carhart notching” (altered bone conduction transmission due to a middle ear effect) that can occur in the presence of CHL (Stenfelt, 2015).…”

Section: Discussionsupporting

confidence: 89%

“…A population-based study in Norway (Austeng et al, 2013) reported that 35% of eight-year-old children with DS had hearing levels greater than 25 dB HL in the better ear, with a higher incidence of SNHL (18%), compared to CHL (16%) and MHL (6%). Paulson et al (2014) reported that 28% of children with DS had mild to profound hearing loss in the worst ear after the insertion of pressure equalizing tubes (PETs). Conversely, Shott et al (2001) reported that 98% of children with DS treated with PETs early and aggressively had normal hearing levels after PET surgery.…”

Section: Introductionmentioning

confidence: 99%

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Wideband acoustic immittance in children with Down syndrome: prediction of middle-ear dysfunction, conductive hearing loss and patent PE tubes

Hunter

Keefe

Feeney

et al. 2017

International Journal of Audiology

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Objective The purpose of this study was to evaluate pressurized wideband acoustic immittance (WAI) tests in children with Down syndrome (DS) and in typically developing children (TD) for prediction of conductive hearing loss (CHL) and patency of pressure equalizing tubes (PETs). Design Audiologic diagnosis was determined by audiometry in combination with distortion-product otoacoustic emissions, 226-Hz tympanometry and otoscopy. WAI results were compared for ears within diagnostic categories (Normal, CHL and PET) and between groups (TD and DS). Study Sample Children with DS (n=40; mean age 6.4 yrs.), and TD children (n=48; mean age 5.1 yrs.) were included. Results Wideband absorbance was significantly lower at 1–4 kHz in ears with CHL compared to NH for both TD and DS groups. In ears with patent PETs, wideband absorbance and group delay (GD) were larger than in ears without PETs between 0.25–1.5 kHz. Wideband absorbance tests performed similarly for prediction of CHL and patent PETs in TD and DS groups. Conclusions Wideband absorbance and group delay revealed specific patterns in both TD children and those with DS that can assist in detection of the presence of significant CHL, assess the patency of PETs, and provide frequency-specific information in the audiometric range.

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Section: Discussionsupporting

confidence: 89%

Section: Introductionmentioning

confidence: 99%

Wideband acoustic immittance in children with Down syndrome: prediction of middle-ear dysfunction, conductive hearing loss and patent PE tubes

Hunter

Keefe

Feeney

et al. 2017

International Journal of Audiology

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“…Some children were managed with ventilation tube insertion ( n = 13) in our study. Outcomes after insertion of ventilation tubes in children with trisomy 21 are variable, and most studies describe preschool and primary school‐aged children . Recurrence of otitis media with effusion after ventilation tube insertion is high and may require two or more procedures .…”

Section: Discussionmentioning

confidence: 99%

“…Outcomes after insertion of ventilation tubes in children with trisomy 21 are variable, and most studies describe preschool and primary school‐aged children . Recurrence of otitis media with effusion after ventilation tube insertion is high and may require two or more procedures . Ventilation tube insertion also has lower rates of complete resolution in children with trisomy 21 (21.4% versus 76.8% in a control group) due to the fluctuating nature of otitis media with effusion in children with trisomy 21 .…”

Section: Discussionmentioning

confidence: 99%

Hearing in school‐aged children with trisomy 21 – results of a longitudinal cohort study in children identified at birth

Yaneza

Hunter

Irwin

et al. 2016

Clinical Otolaryngology

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Otitis media with effusion was the commonest cause of hearing impairment; effusions may fluctuate through the pre-teenaged years, and thus, hearing aids are beneficial. Ventilation tube insertion and bone-conducting hearing aids were useful when ear-level hearing aids were not tolerated. Mixed hearing loss occurred in later years as sensorineural hearing loss developed on a background of otitis media with effusion.

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“…Ear problems such as inner ear dysplasia/hypoplasia, vestibular malformations, lateral semicircular anomalies, and conductive, mixed or neurosensory hearing loss are common in patients with DS (Blaser et al, ). Moreover, a high prevalence of chronic otitis media with effusion (≥ 60%) has also been reported (Maris et al, ), with hearing loss recovered via insertion of grommets (tympanostomy tubes) (Paulson et al, ).…”

Section: Clinical Features Of Dsmentioning

confidence: 99%

Down syndrome—A narrative review with a focus on anatomical features

Arumugam

Raja²,

Venugopalan³

et al. 2015

Clinical Anatomy

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Down syndrome (DS) is the most common aneuploidy of chromosome 21, characterized by the presence of an extra copy of that chromosome (trisomy 21). Children with DS present with an abnormal phenotype, which is attributed to a loss of genetic balance or an excess dose of chromosome 21 genes. In recent years, advances in prenatal screening and diagnostic tests have aided in the early diagnosis and appropriate management of fetuses with DS. A myriad of clinical symptoms resulting from cognitive, physical, and physiological impairments caused by aberrations in various systems of the body occur in DS. However, despite these impairments, which range from trivial to fatal manifestations, the survival rate of individuals with DS has increased dramatically from less than 50% during the mid-1990s to 95% in the early 2000s, with a median life expectancy of 60 years reported recently. The aim of this narrative review is to review and summarize the etiopathology, prenatal screening and diagnostic tests, prognosis, clinical manifestations in various body systems, and comorbidities associated with DS. Clin. Anat. 29:568-577, 2016. © 2015 Wiley Periodicals, Inc.

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Outcomes of tympanostomy tube placement in children with Down syndrome—A retrospective review

Cited by 35 publications

References 18 publications

Wideband acoustic immittance in children with Down syndrome: prediction of middle-ear dysfunction, conductive hearing loss and patent PE tubes

Wideband acoustic immittance in children with Down syndrome: prediction of middle-ear dysfunction, conductive hearing loss and patent PE tubes

Hearing in school‐aged children with trisomy 21 – results of a longitudinal cohort study in children identified at birth

Down syndrome—A narrative review with a focus on anatomical features

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