Outcomes of transcatheter tricuspid valve intervention by right ventricular function: a multicentre propensity-matched analysis

Schlotter, Florian; Miura, Mizuki; Kresoja, Karl‐Patrik; Alushi, Brunilda; Alessandrini, Hannes; Attinger‐Toller, Adrian; Besler, Christian; Biasco, Luigi; Braun, Daniel; Brochet, Éric; Connelly, Kim A.; Bruijn, Sabine de; Denti, Paolo; Estévez‐Loureiro, Rodrigo; Fam, Neil; Gavazzoni, Mara; Himbert, Dominique; Ho, Edwin; Juliard, Jean‐Michel; Kalbacher, Daniel; Kaple, Ryan; Kreidel, Felix; Latib, Azeem; Lubos, Edith; Ludwig, Sebastian; Mehr, Michael; Moñivas, Vanessa; Nazif, Tamim; Nickenig, Georg; Pedrazzini, Giovanni; Pozzoli, Alberto; Praz, Fabien; Puri, Rishi; Rodés‐Cabau, Josep; Rommel, Karl‐Philipp; Schäfer, Ulrich; Schöfer, Joachim; Sievert, Horst; Tang, Gilbert H.L.; Thiele, Holger; Unterhuber, Matthias; Vahanian, Alec; Bardeleben, Ralph Stephan von; Roeder, Maximilian von; Webb, John G.; Weber, Marcel; Wild, Mirjam G.; Windecker, Stephan; Züber, Michel; Hausleiter, Jörg; Maisano, Francesco; Leon, Martin B.; Hahn, Rebecca T.; Lauten, Alexander; Taramasso, Maurizio; Lurz, Philipp

doi:10.4244/eij-d-21-00191

Cited by 54 publications

(32 citation statements)

References 32 publications

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“… 8 A recent Trivalve registry analysis suggested that patients with moderate RV dysfunction who underwent TTVI had better survival compared with patients with preserved or severely reduced RV function. 9 A finding that has implications for patient selection and timing of TTVr. RV contraction patterns can also be characterized by cardiac magnetic resonance imaging, and severe global RV dysfunction was a strong predictor of mortality in patients undergoing TTVr.…”

Section: Discussionmentioning

confidence: 99%

Acute Afterload Mismatch After Transcatheter Tricuspid Valve Repair

et al. 2022

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Section: Discussionmentioning

confidence: 99%

Acute Afterload Mismatch After Transcatheter Tricuspid Valve Repair

et al. 2022

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“…Similarly, the presence of RV dysfunction has been shown to be a risk factor associated with adverse outcome in patients with TR and in tricuspid valve surgery, as underlined previously ( 29 , 40 ). Schlotter et al ( 41 ) decided to analyze the clinical impact of RV dysfunction in patients undergoing TTVI from the TriValve registry, in order to try and shed some light on favorable responders and patient selection. Patients from the TTVI cohort were compared to patients treated conservatively, and the whole population was further stratified in three subgroups according to longitudinal RV function expressed by the tricuspid annular plane systolic excursion (TAPSE): preserved (TAPSE >17 mm), mid-range (TAPSE 13–17 mm) and reduced RV function (TAPSE <13 mm).…”

Section: Transcatheter Treatmentmentioning

confidence: 99%

Transcatheter and surgical treatment of tricuspid regurgitation: Predicting right ventricular decompensation and favorable responders

Sala

Beneduce²

2022

Front. Cardiovasc. Med.

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Isolated tricuspid regurgitation (TR) has gained increasing recognition in recent years both in the surgical and in the cardiological community. Left untreated, isolated TR significantly worsens survival. Despite being a strong predictor of negative prognosis, interventions to correct TR are rarely performed due to increased surgical risk and late patient presentation. Recently, the ultimate focus has been on patient selection, surgical or transcatheter indication, and correct timing. Furthermore, of paramount importance is the identification of predictors of outcome following treatment, in order to discriminate between favorable and unfavorable responders and guide the decision-making process of the most adequate treatment for every patient.

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“…39 Of note, tricuspid annular plane systolic excursion (TAPSE) and systolic pulmonary artery pressure showed only a slight influence on procedural and clinical outcome. 68,69 These findings suggest that TAPSE alone is not sufficient to assess RV function, and all the other common parameters commonly used to assess RV function (S ′ velocity by tissue Doppler imaging, RV free-wall longitudinal strain, RV fractional area change, and 3D RV ejection fraction) are extremely load-dependent and not accurate in the setting of severe TR.…”

Section: Too Early Too Late: the 'Right' Timing For Intervention In T...mentioning

confidence: 99%

Challenges and future perspectives of transcatheter tricuspid valve interventions: adopt old strategies or adapt to new opportunities?

Russo

Taramasso

Pedicino

et al. 2021

European J of Heart Fail

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Tricuspid regurgitation (TR) is a highly prevalent valvular heart disease and is associated with an increased risk of cardiovascular events and death at long-term follow-up. Functional TR accounts for over 90% of TR and is mainly due to annular or right ventricular dilatation. Most often, TR is observed in patients with left-sided valvular heart disease (with or without previous surgical correction) and pulmonary hypertension. Isolated TR is less frequent, though burdened by high surgical mortality. This, together with an incomplete understanding of the disease, has brought to a significant undertreatment in spite of the growing evidence of the impact of severe TR on mortality. Moreover, uncertainties about the appropriate timing for intervention and the predictors of procedural success have contributed to limit TR treatment. Transcatheter tricuspid valve replacement or repair interventions represent novel and less invasive alternatives to surgery and have shown early promising results. The purpose of this review is to provide a complete and updated overview of TR pathology with a special focus on current percutaneous treatment options, future challenges and directions.

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Outcomes of transcatheter tricuspid valve intervention by right ventricular function: a multicentre propensity-matched analysis

Cited by 54 publications

References 32 publications

Acute Afterload Mismatch After Transcatheter Tricuspid Valve Repair

Acute Afterload Mismatch After Transcatheter Tricuspid Valve Repair

Transcatheter and surgical treatment of tricuspid regurgitation: Predicting right ventricular decompensation and favorable responders

Challenges and future perspectives of transcatheter tricuspid valve interventions: adopt old strategies or adapt to new opportunities?

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