Outcomes of transcatheter mitral valve replacement for degenerated bioprostheses, failed annuloplasty rings, and mitral annular calcification

Yoon, Sung Han; Whisenant, Brian; Bleiziffer, Sabine; Delgado, Victoria; Dhoble, Abhijeet; Schofer, Niklas; Eschenbach, Lena Katharina; Bansal, Eric; Murdoch, D.; Ancona, Marco; Schmidt, Tobias; Yzeiraj, Ermela; Vincent, Flavien; Niikura, Hiroki; Kim, Won Keun; Asami, Masahiko; Unbehaun, Axel; Hirji, Sameer; Fujita, Buntaro; Silaschi, Miriam; Tang, Guping; Kuwata, Shingo; Wong, S. Chiu; Frangieh, Antonio H.; Barker, Colin M.; Davies, James E.; Lauten, Alexander; Deuschl, Florian; Nombela‐Franco, Luis; Rampat, Rajiv; Nicz, Pedro Felipe Gomes; Masson, Jean Bernard; Wijeysundera, Harindra C.; Sievert, Horst; Blackman, Daniel J.; Gutiérrez‐Ibañes, Enrique; Sugiyama, Daisuke; Chakravarty, Tarun; Hildick‐Smith, David; Brito, Fábio Sândoli de; Jensen, Christoph; Jung, Christian; Smalling, Richard W.; Arnold, Martin; Redwood, Simon; Kasel, Albert Markus; Maisano, Francesco; Treede, Hendrik; Ensminger, Stephan; Kar, Saibal; Kaneko, Tsuyoshi; Pilgrim, Thomas; Sorajja, Paul; Belle, Éric Van; Prendergast, Bernard; Bapat, Vinayak; Modine, Thomas; Schöfer, Joachim; Frerker, Christian; Kempfert, Joerg; Attizzani, Guilherme F.; Latib, Azeem; Schäefer, Ulrich; Webb, John G.; Bax, Jeroen J.; Makkar, Raj

doi:10.1093/eurheartj/ehy590

Cited by 282 publications

(275 citation statements)

References 30 publications

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“…Left ventricular outflow obstruction (LVOTO) is a known possible complication of TMVR. In the TMVR registry, LVOTO was observed in 7.1% of patients with a higher incidence of 39.7% in MAC patients . This complication leads to more frequent need for intra‐procedural alcohol septal ablation in the MAC group.…”

Section: Mitral Annular/valve Calcification and Degenerative Mitral Smentioning

confidence: 99%

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Degenerative mitral valve stenosis: Diagnosis and management

et al. 2019

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Mitral stenosis (MS) is a common valvular disease characterized by narrowing of the mitral valve orifice and a reduction in mitral valve area (MVA). While rheumatic MS (RMS) is frequently encountered in young individuals in developing countries, degenerative MS (DMS) is seen in the elderly in developed countries and its prevalence is increasing. DMS is usually a late presentation of mitral annular calcification (MAC). Accurate assessment of MVA in patients with MAC is challenging due to the alterations in the atrial and valvular structures as well as the presence of other comorbidities in this aging population. We will review the epidemiology, etiology, pathophysiology, diagnostic assessment, and management of DMS and compare the findings with RMS. The latest therapeutic approaches, including medical, surgical, and transcatheter valvular interventions, will be discussed.

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Section: Mitral Annular/valve Calcification and Degenerative Mitral Smentioning

confidence: 99%

“…In the TMVR registry, LVOTO was observed in 7.1% of patients with a higher incidence of 39.7% in MAC patients. 59 This complication leads to more frequent need for intra-procedural alcohol septal ablation in the MAC group. All-cause 30-day mortality was 34.5%, which was significantly higher in the MAC group.…”

Section: Other Approaches To Severe Mac Managementmentioning

confidence: 99%

Degenerative mitral valve stenosis: Diagnosis and management

et al. 2019

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“…In adults, a recent study reported on transcatheter mitral valve implantation of patients with degenerated bioprostheses (valve‐in‐valve), failed annuloplasty rings (valve‐in‐ring), and severe mitral annular calcification (valve‐in‐mitral annular calcification). They found that all‐cause mortality was higher after “valve‐in‐mitral annular calcification” compared with “valve‐in‐ring” and “valve‐in‐valve” at 30 days (34.5% vs. 9.9% vs. 6.2%; log‐rank p < .001) …”

Section: Discussionmentioning

confidence: 99%

Transcatheter mitral valve‐in‐valve implantation in a pediatric patient

Momenah

Alsahari²,

Eltayeb³

et al. 2019

Cathet Cardio Intervent

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“…2 Recently, in TMVR multicentre registry, procedural and clinical outcomes of the valve in valve (ViV), valve in ring (ViR), and ViMAC were reported by Yoon et al 3 In this registry, PVL closure was more frequently performed in the ViR group compared with ViV and ViMAC groups (7.8 vs. 2.2 vs. 0.0%; p = 0.006). 3 We have some comments regarding the factors, which might potentially reduce the incidence of PVL in ViMAC. Firstly, assessment of MAC is important and often requires integration of multimodality imaging.…”

Section: Dear Editormentioning

confidence: 99%