Outcomes of staged lingual mucosal graft urethroplasty for redo hypospadias repair

Aldaqadossi, Hussein; Shaker, Hossam; Youssof, Hamada Ahmed; Kotb, Y.; El-Adawy, Mahmoud Shoukry

doi:10.1016/j.jpurol.2019.06.007

Cited by 10 publications

(6 citation statements)

References 29 publications

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“…e properties of buccal mucosa such as the absence of hair follicle, highly vascular lamina propria promoting early in growth, wet environment compatibility [12], and ease of harvest with a concealed donor site scar makes it a near ideal substitute for urethra. e incidence of graft contracture in BMG urethroplasty varies from 3 to 22.5% in various studies [13][14][15][16][17][18]. Oral mucosal grafts are also used in the ocular reconstructive Advances in Urology surgeries [19].…”

Section: Discussionmentioning

confidence: 99%

Evaluation of the Extent of Primary Buccal Mucosal Graft Contracture in Augmentation Urethroplasty for Stricture Urethra: A Prospective Observational Study at a Tertiary Healthcare Centre

Bhalaguruiyyan

Murugan

Alakhananda

et al. 2021

Advances in Urology

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Introduction. Buccal mucosal graft (BMG) urethroplasty is considered as gold standard in the treatment of urethral stricture disease. The successful outcome after BMG urethroplasty varies between 66 and 99%. One of the possible causes for failure is BMG contracture. Primary BMG contracture rate is poorly understood and unreported. The present study aimed to evaluate the extent of contracture of buccal mucosa immediately after harvesting. Materials and Methods. This was a prospective observational study conducted in the Department of Urology at our institute between January 2016 and December 2019. All patients with urethral stricture disease undergoing BMG urethroplasty for the first time were enrolled in the study after obtaining informed consent. Demographic and patient clinical profile was noted. Based on the intraoperative urethral stricture size, the preharvest graft was marked on the buccal mucosa and the size was calculated. Postharvest unstretched size of the graft was measured immediately after graft removal from the oral cavity. Alteration in BMG size was analysed using paired t-test. Results. Forty-four patients were included in the study. Mean age of the patient was 53.6 years. Mean stricture length was 7.45 cm (range 4–12 cm). Mean pre- and postharvest BMG size was 8.3 × 1.5 cm and 7.6 × 1.3 cm, respectively. There was a 8.4% decrease in length and 9.5% decrease in width of the buccal mucosal graft. Conclusion. Primary buccal mucosal graft contracture is around 8.4% in length and 9.5% in width. It would be better to mark wider than necessary while harvesting buccal mucosa so that tension-free anastomosis is performed.

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Section: Discussionmentioning

confidence: 99%

Evaluation of the Extent of Primary Buccal Mucosal Graft Contracture in Augmentation Urethroplasty for Stricture Urethra: A Prospective Observational Study at a Tertiary Healthcare Centre

Bhalaguruiyyan

Murugan

Alakhananda

et al. 2021

Advances in Urology

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“…However, many complications are encountered. The removal of this tissue has disadvantages in more than 80% of patients [ 61 ], such as pain, numbness, submucosal scars, dry mouth, lesions [ 62 ], neurosensitive defects, discomfort [ 63 ], disorders of the opening of the mouth (contracture), and risks of oral infections. In addition, compared to the autologous urethral tissue, these substitutes have a limited barrier function for urine, a particularly toxic product.…”

Section: Common Penile Pathologies Anomalies and Treatmentsmentioning

confidence: 99%

Tissue Engineering for Penile Reconstruction

Elia,

Caneparo,

McMartin

et al. 2024

Bioengineering

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The penis is a complex organ with a development cycle from the fetal stage to puberty. In addition, it may suffer from either congenital or acquired anomalies. Penile surgical reconstruction has been the center of interest for many researchers but is still challenging due to the complexity of its anatomy and functionality. In this review, penile anatomy, pathologies, and current treatments are described, including surgical techniques and tissue engineering approaches. The self-assembly technique currently applied is emphasized since it is considered promising for an adequate tissue-engineered penile reconstructed substitute.

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“…Lingual mucosal grafts, buccal mucosal grafts and skin grafts can be used for re-do hypospadias repairs in this group of patients. 4,5 The choice of graft depends on the preference of the surgeons. Skin grafts which are very easy to harvest are commonly used as an onlay graft or tubularised graft to create a new urethra.…”

Section: Depending On Previous Surgeries and Circumcision Local Tissu...mentioning

confidence: 99%

“…In these cases, grafting procedures or island flaps are mostly used. Lingual mucosal grafts, buccal mucosal grafts and skin grafts can be used for re‐do hypospadias repairs in this group of patients 4,5 . The choice of graft depends on the preference of the surgeons.…”

Section: Introductionmentioning

confidence: 99%