2019
DOI: 10.1016/j.lungcan.2018.11.019
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Outcomes of Stage III NSCLC with occult primary vs. known primary lesions

Abstract: Objectives: Occult primary non-small cell lung cancer (OP-NSCLC) involving mediastinal lymph nodes without an identifiable primary tumor is a rare presentation, with little known about how outcomes compare to typical Stage III NSCLC. We reviewed our experience treating OP-SCLC with definitive radiotherapy and compared outcomes to a contemporary cohort of stage III NSCLC patients. Materials and Methods: We reviewed 605 patients with stage III NSCLC staged with PET-CT and treated with definitive radiotherapy b… Show more

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“…26 The aim of our study was to investigate the relationship between NS and survival among patients with occult pN2a1 disease and to compare that with the relationship between SF and survival, as SF has been shown to be associated with the most-favorable outcomes. 27 Although we observed some evidence of worse DFS among those treated with NS, compared with SF, differences between groups did not meet the conventional level of statistical significance. We have demonstrated through this retrospective analysis that, regardless of preoperative treatment, long-term survival is similar when pN2a1 disease is found postoperatively.…”
Section: Discussionmentioning
confidence: 55%
“…26 The aim of our study was to investigate the relationship between NS and survival among patients with occult pN2a1 disease and to compare that with the relationship between SF and survival, as SF has been shown to be associated with the most-favorable outcomes. 27 Although we observed some evidence of worse DFS among those treated with NS, compared with SF, differences between groups did not meet the conventional level of statistical significance. We have demonstrated through this retrospective analysis that, regardless of preoperative treatment, long-term survival is similar when pN2a1 disease is found postoperatively.…”
Section: Discussionmentioning
confidence: 55%