Outcomes of ST-segment elevation myocardial infarction survivors complicated by out-of-hospital cardiac arrest: a single-center surveillance study.

Velibey, Yalçın; Parsova, Kemal Emrecan; Ceylan, Ufuk Sadık; Güzelburç, Özge; Demir, Koray; Yıldız, Ufuk; Şafak, Aylin; Akdeniz, Evliya; Güvenç, Tolga Sinan; Bozbeyoğlu, Emrah; Tekkeşin, Ahmet İlker

doi:10.5543/tkda.2018.32657

Cited by 4 publications

(9 citation statements)

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“…After removing duplicates (n = 5296), the remaining 10 051 records were screened on titles and abstracts. Of the resulting 854 full-text articles, 38 studies were included in the final qualitative and quantitative analysis. A total of 21 studies with 11 800 patients were used for KM-based meta-analysis, whereas 33 studies with 16 933 patients were used for aggregate data meta-analysis.…”

Section: Resultsmentioning

confidence: 99%

“…Of the resulting 854 full-text articles, 38 studies were included in the final qualitative and quantitative analysis. A total of 21 studies with 11 800 patients were used for KM-based meta-analysis, whereas 33 studies with 16 933 patients were used for aggregate data meta-analysis. eFigure 1 in the Supplement outlines the study selection process.…”

Section: Resultsmentioning

confidence: 99%

“…The characteristics of the included studies are given in Table 1, and a detailed summary of the included studies can be found in eTable 1 in the Supplement. The studies were conducted on 4 continents: Europe (n = 20), North America (n = 8), Asia (n = 6), and Australia (n = 4).…”

Section: Resultsmentioning

confidence: 99%

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Long-term Survival After Out-of-Hospital Cardiac Arrest

et al. 2022

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IMPORTANCE Data on long-term survival beyond 12 months after out-of-hospital cardiac arrest (OHCA) of a presumed cardiac cause are scarce.OBJECTIVE To investigate the long-term survival of adult patients after surviving the initial hospital stay for an OHCA.DATA SOURCES A systematic search of the EMBASE and MEDLINE databases was performed from database inception to March 25, 2021.STUDY SELECTION Clinical studies reporting long-term survival after OHCA were selected based on predefined inclusion and exclusion criteria according to a preregistered study protocol.DATA EXTRACTION AND SYNTHESIS Patient data were reconstructed from Kaplan-Meier curves using an iterative algorithm and then pooled to generate survival curves. As a separate analysis, an aggregate data meta-analysis was performed. MAIN OUTCOMES AND MEASURESThe primary outcome was long-term survival (>12 months) after OHCA for patients surviving to hospital discharge or 30 days after OHCA. RESULTSThe search identified 15 347 reports, of which 21 studies (11 800 patients) were included in the Kaplan-Meier-based meta-analysis and 33 studies (16 933 patients) in an aggregate data meta-analysis. In the Kaplan-Meier-based analysis, the median survival time for patients surviving to hospital discharge was 5.0 years (IQR, 2.3-7.9 years). The estimated survival rates were 82.8% (95% CI, 81.9%-83.7%) at 3 years, 77.0% (95% CI, 75.9%-78.0%) at 5 years, 63.9% (95% CI, 62.3%-65.4%) at 10 years, and 57.5% (95% CI, 54.8%-60.1%) at 15 years. Compared with patients with a nonshockable initial rhythm, patients with a shockable rhythm had a lower risk of long-term mortality (hazard ratio, 0.30; 95% CI, 0.23-0.39; P < .001). Different analyses, including an aggregate data meta-analysis, confirmed these results. CONCLUSIONS AND RELEVANCEIn this comprehensive systematic review and meta-analysis, long-term survival after 10 years in patients surviving the initial hospital stay after OHCA was between 62% and 64%. Additional research is needed to understand and improve the long-term survival in this vulnerable patient population.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

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Long-term Survival After Out-of-Hospital Cardiac Arrest

et al. 2022

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“…In a recent publication [2] there is no distinction made between comatose and conscious OOHCA survivors, nor is there such a distinction reported in a Turkish study from October 2018 [3].…”

Section: Discussionmentioning

confidence: 93%

Immediate coronary intervention in comatose survivors of out of hospital cardiac arrest: Outcomes from two tertiary, 24/7 primary percutaneous coronary intervention centres in UK

Hailan¹,

Khatun²,

Ionescu³

et al. 2019

Interventional-Cardiology

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Background: There is a relative lack of data regarding the outcomes of comatose patients who present to the cath lab intubated and ventilated.Aim of the study: To analyse patient-and procedural-related variables at the time of emergency percutaneous coronary intervention (PCI) in patients who arrive in the cath lab intubated and ventilated and establish their relation to 30-day mortality.Setting: Two regional tertiary cardiac centres, the University Hospital of Wales in Cardiff and Morriston Cardiac Centre in Swansea. Methods:We included all consecutive patients between 01/03/2007 and 31/03/2014 who had PCI to a native coronary artery while being intubated and ventilated, and we documented their clinical and interventional features using the cath lab databases of the 2 institutions. We correlated these features with survival status at 30 days. Results:We included 133 patients (71% M), mean age 63.7 years (61.7-65.8; 95% confidence interval -CI) who had primary PCI for ST-segment elevation myocardial infarction (STEMI) (62%), PCI for unstable angina (UA)/ Non-STEMI (NSTEMI) (31%) or rescue PCI (8%). Mortality was 37% at 30 days, with most deaths occurring during the first week after PCI. The following features correlated with mortality (p values): History of myocardial infarction (MI) (0.026); age (0.021), cardiogenic shock (0.007), reduced pre-procedural Thrombolysis in myocardial infarction (TIMI) flow in the culprit artery (0.020), number of coronary arteries with stenosis >70% (0.03), incomplete revascularisation (0.01). In multi-variate analysis only cardiogenic shock (p=0.008; OR 4.552), incomplete revascularisation (p<0.001; OR 7.554) and

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“…-Eight studies identified as Cohort (including two identified as a retrospective cohort and five identified as a prospective cohort) [20][21][22][23][24][25][26][27].…”

Section: : Total Number Of Articles After Applying Inclusion/exclusimentioning

confidence: 99%

Major Adverse Cardiovascular Events: An Inevitable Outcome of ST-elevation myocardial infarction? A Literature Review

Poudel¹,

Tejpal²,

Rashid³

et al. 2019

Cureus

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Major adverse cardiovascular events (MACE) remain the major cause of mortality and morbidity in patients with STEMI (ST-elevation myocardial infarction). The current literature is aimed to analyze the occurrence of MACE following STEMI irrespective of treatment provided, and follow up after the first diagnosis of STEMI. A PubMed search for Studies of STEMI identified 24,244 articles. After applying our inclusion/exclusion criteria, we found out 75 articles of relevance wherein MACE and its components were considered to be the primary endpoint. These 75 articles included eight Cohort Studies, 13 clinical trials including five randomized controlled trials (RCT), one case-control Study, one cross-sectional study, one review article, and 51 other observational studies. Our analysis shows that MACE remains one of the strongest adverse outcomes among STEMI patients. The current literature review found out the incidence of MACE was 4.2 % to 51% irrespective of the mode of treatment, and follow-ups lasting up to 10 years from the time of STEMI diagnosis.

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Outcomes of ST-segment elevation myocardial infarction survivors complicated by out-of-hospital cardiac arrest: a single-center surveillance study.

Cited by 4 publications

References 0 publications

Long-term Survival After Out-of-Hospital Cardiac Arrest

Long-term Survival After Out-of-Hospital Cardiac Arrest

Immediate coronary intervention in comatose survivors of out of hospital cardiac arrest: Outcomes from two tertiary, 24/7 primary percutaneous coronary intervention centres in UK

Major Adverse Cardiovascular Events: An Inevitable Outcome of ST-elevation myocardial infarction? A Literature Review

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