2010
DOI: 10.1016/j.jcms.2009.03.015
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Outcomes of prophylactic antibiotics following surgery for zygomatic bone fractures

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Cited by 53 publications
(51 citation statements)
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“…Several methods to control the immediate inflammatory response associated with head and neck surgery have been described and used, including the use of drugs such as analgesics [1][2][3], corticosteroids [3], antibiotics [4], and proteolytic enzymes [5], laser application [6], or physical therapeutic methods like cryotherapy [7] or manual lymph drainage (MLD) [8]. No single modality of management significantly prevents and/or significantly reduces the occurrence of swelling, pain and trismus without potential undesirable side effects.…”
Section: Introductionmentioning
confidence: 99%
“…Several methods to control the immediate inflammatory response associated with head and neck surgery have been described and used, including the use of drugs such as analgesics [1][2][3], corticosteroids [3], antibiotics [4], and proteolytic enzymes [5], laser application [6], or physical therapeutic methods like cryotherapy [7] or manual lymph drainage (MLD) [8]. No single modality of management significantly prevents and/or significantly reduces the occurrence of swelling, pain and trismus without potential undesirable side effects.…”
Section: Introductionmentioning
confidence: 99%
“…In accordance with prior operational definitions, we defined preoperative prophylaxis as antibiotic therapy received prior to 2 hours before surgery, perioperative prophylaxis as antibiotics administered within 2 hours before surgery to 24 hours after surgery, and postoperative prophylaxis as antibiotic coverage beyond the perioperative window (longer than 24 hours after surgery) . Because several studies reported that prophylaxis was initiated from hospital admission through the perioperative period, but did not specify the length of time prior to surgery, we used an approach similar to Shridharani et al and considered this to be a combination of pre‐ and perioperative prophylaxis . Additionally, if studies explicitly stated that patients received preoperative antibiotic prophylaxis (in addition to perioperative antibiotics), they were placed in the pre‐ + perioperative group .…”
Section: Methodsmentioning
confidence: 99%
“…In summary, based on these recent 25,27 and previously reviewed studies 26,28,29 from mandibular fractures and contaminated head and neck cases 24 with similar outcomes, antibiotics in excess of those administered during the 24-hour perioperative period for maxillofacial injury do not appear to reduce wound infection (Table 1) and should be discontinued at 24 hours postoperatively.…”
Section: Maxillofacial and Neck Injuriesmentioning
confidence: 97%
“…27 The authors studied 134 patients and used a protocol of no antibiotics if reduction was performed without plating; oral amoxicillin/clavulanate or cefuroxime or an ampicillin/dicloxacillin combination preoperatively and for two doses postoperatively if extra-oral reduction with plating was required; and the same regimen plus metronidazole if intraoral reduction with plating was required. This approach resulted in a 2% infection rate (higher than the previously quoted 0%), all in the intraoral fixation group.…”
Section: Maxillofacial and Neck Injuriesmentioning
confidence: 99%