Background: COVID-19 epidemic is one of the major health problems all over the world due to its amazing spreading power and potential damage. Given the increasing prevalence of the disease, identifying the care needs and preferences of patients will play a very important role in providing effective training and caring programs for them. This study aimed to explain the Preferences and needs of care based on the experiences of people with COVID-19.Methods: This qualitative study was carried out over a period of 2 months in medical and recovery units of COVID-19 referral hospitals in Tehran, the capital of Iran in 2020. The Participants consisted of 15 COVID-19 patients selected through purposive sampling.Results: The results were classified into five main categories as “Access to desirable care and comfort services”, “Access to education and information from credible sources”, “Access to specialized care” “Support-social needs” and “Need for deep emotional interactions”.Conclusions: According to the results, identifying priorities and care needs from the perspective of patients with COVID-19 can help improve knowledge, reduce unrealistic patient concerns, and improve emotional interactions between patients and health care providers.