Outcomes of pediatric living donor kidney transplantation: A single‐center experience

Abstract

Renal transplantation is the treatment of choice for children with ESRD offering advantages of improved survival, growth potential, cognitive development, and quality of life. The aim of our study was to compare the outcomes of LDKT vs DDKT performed in children at a single center. Retrospective chart review of pediatric patients who underwent kidney transplantation from 2005 to 2014 was performed. Ninety-one renal transplants were accomplished, and 31 cases (38.27%) were LDKT, and in 96.7% of the cases, the graft was obtained through laparoscopy. Thirty-four receptors weighted <25 kg. LDKT group had statistically significant lower cold ischemia times than DDKT one. Complication rate was 9.67% for LDKT and 18.33% for DDKT. eGFR was better in LDKT. Patient survival rate was 100% for LDKT and 98.3% for DDKT, and graft survival rate was 96.7% for LDKT and 88.33%-80% for DDKT at a year and 5 years. Our program of pediatric kidney transplantation has achieved optimal patient and graft survival rates with low rate of complications. Living donor pediatric kidney transplants have higher patient and better graft survival rates than deceased donor kidney transplants.

Intraoperative hemodynamic factors predicting early postoperative renal function in pediatric kidney transplantation

“…Given these considerations, pediatric recipient transplantation with adult donor kidneys is common, particularly so in living donor transplantations . The intraoperative management of adult donor pediatric recipient transplantations is delicate, especially for smaller recipients.…”

“…Given these considerations, pediatric recipient transplantation with adult donor kidneys is common, particularly so in living donor transplantations. 3 The intraoperative management of adult donor pediatric recipient transplantations is delicate, especially for smaller recipients. Surgery is technically challenging due to vessel size mismatch at anastomoses, and the donor organ and recipient patient have potentially divergent hemodynamic requirements.…”

Good outcome of the single‐center pediatric kidney transplant program in Abu Dhabi

“…The renal transplantation at our center was from living donor, majority from LRD (parents). Living donor transplant is reported to have better survival outcomes for pediatric recipients irrespective of donor age and should be recommended whenever possible . Immunosuppression protocols followed at our center are in accordance with the current practices and guidelines followed across the world…”

“…Living donor transplant is reported to have better survival outcomes for pediatric recipients irrespective of donor age and should be recommended whenever possible. 13,17,18 Immunosuppression protocols followed at our center are in accordance with the current practices and guidelines followed across the world. 12,13 Most recipients in our study had a negative history of post-trans- The graft survival rates observed at our center were 96.7% probabilities for recipients from LRD were 94%, 83%, and 77% at 1, 5, and 7 years post-transplant, respectively.…”

The choice between deceased‐ vs living‐donor renal transplantation in children: Analysis of data from a Belgian tertiary center

“…The incidence of living donation in our center is lower than that reported in the literature. In Europe, the LD transplantation accounts for around 40% of all pediatric KT . Van Huis et al reported a difference in the proportion of living kidney donation between children from the Netherlands and Belgium: 48% vs. 26%, respectively .…”