Outcomes of patients with histologically proven acute acalculous cholecystitis

Abstract

AAC more commonly occurs in older patients and those with COAD. The operative outcomes and complications of AAC treated by cholecystectomy are similar to cases of acute calculous cholecystitis.

Current status and therapeutic strategy of acute acalculous cholecystitis: Japanese nationwide survey in the era of the Tokyo guidelines

“…The 7.04% occurrence rate of AAC in this study was similar to that reported in the previous series using similar criteria for AAC. 7,12 However, several studies reported a higher incidence of AAC than that in the present study. 9,11 Most of the studies used identical diagnostic criteria for AAC to this study, such as no stones or sludges in the gallbladder on imaging or pathological findings, although the diagnostic criteria of AC were different among studies.…”

“…We obtained a similar AAC occurrence rate to previous studies where AC was diagnosed pathologically, accordingly the TG18 diagnostic criteria could be equal to the pathological diagnosis. 7,12 Yokoe et al reported the distribution of the TG severity grade in their Japan-Taiwan collaborative study of AC and showed 36.4%, 46.0%, and 17.6% of patients were diagnosed as Grade I, II, and III, respectively. 19 This severity grade is equivalent to that of AAC patients in the present study.…”

“…On the other hand, several studies have reported that AAC could occur in healthy individuals with a prognosis similar to ACC, and most of such patients with AAC are outpatients rather than inpatients. 7,11,12 As a matter of fact, the pathophysiology of AAC is not elucidated because its pathogenesis is complex and multifactorial, including anatomical abnormalities, gallbladder ischemia, bile stasis, clinically ill status, and so on. 2 The Tokyo Guidelines (TG) were published in 2007 to standardize the diagnostic criteria and treatment strategy of AC and acute cholangitis, which has been revised two times to become more prevalent worldwide.…”

Prognostic Significance of Ultrasound Findings of Acute Acalculous Cholecystitis for Elderly Long-Term Bedridden Patients

“…In our study, all the AAC patients were found to have atherosclerotic vascular-associated diseases, such as hypertension, diabetes, apoplexy, or ischemic heart disease. Studies have shown that atherosclerosis and increased blood viscosity in the elderly aggravates the ischemia of the gallbladder wall (23). In particular, diffuse damage to the wall of small blood vessels, which narrows and obstructs the arterial lumen, and damage to gallbladder mucosa significantly increase the risk of AAC (16,(24)(25)(26).…”

Toxocarosis y colecistitis aguda alitiásica: ¿consecuencia o coincidencia?

“…La CAA se ha asociado a mal pronóstico por el retraso en el diagnóstico y tratamiento, así como a la presentación en pacientes graves o con co-morbilidades [33][34][35][36] . De las publicaciones disponibles, es evidente que la CAA puede presentarse en niños aparentemente sanos 37 , en pacientes con patologías médicas [38][39][40] y quirúrgicas 41 , en infecciones graves de distinta etiología [42][43][44] , como también en infecciones banales 45 .…”