Outcomes of patients with acute coronary syndromes and prior percutaneous coronary intervention: a pooled analysis of three randomized clinical trials

Abstract

Patients with prior PCI who present with non-ST-segment elevation ACS have a lower mortality rate than those without prior PCI.

Management patterns of non-ST segment elevation acute coronary syndromes in relation to prior coronary revascularization

“…Significantly lower mortality rates at 30 days and 180 days were observed in the prior PCI group. 28 In the present study of less selected ACS patients, the group with prior PCI had lower unadjusted rates of in-hospital mortality and death/(re-)MI. In contrast, Sanchis et al 29 found that prior PCI is an adverse prognosticator among NSTE-ACS patients with normal troponin levels.…”

l-carnitine as an Adjunct Therapy to Percutaneous Coronary Intervention for Non-ST Elevation Myocardial Infarction

“…Several randomized trials have demonstrated that patients presenting with an ACS and who subsequently undergo routine angiography and revascularization by PCI have improved outcomes compared with patients who were not treated with PCI [5,8,9]. Early reperfusion of totally occluded coronary arteries reduces the infarct size, cardiac mortality rates and in-hospital events.…”

“…Patients who met one or more the following criteria were excluded from the study: (1) coronary artery stenosis <70%; (2) ST elevation myocardial infarction; (3) plasma creatinine >2.5 mg/dl; (4) stroke within 3 months; (5) terminal illnesses such as advanced cancer.…”

“…However, PCI offers significant clinical benefits in patients with acute coronary syndrome (ACS) [5]. In the last decade, the percentage of patients with non-ST elevation myocardial infarction (NSTEMI) managed with PCI has steadily increased, and now stands at approximately 50% [6].…”

miR-96 and miR-183 differentially regulate neonatal and adult postinfarct neovascularization

“…Myocardial infarction (MI) is a major threat to human health and contributes to substantial morbidity and mortality worldwide ( 1 , 2 ). Conventional treatments aim to promote reoxygenation of the infarcted myocardium, for example, through interventions, such as coronary artery bypass surgery or percutaneous coronary intervention, with the goal of limiting infarct expansion and therefore progression to heart failure ( 3 – 5 ).…”