Outcomes of nonsurgical periodontal therapy in severe generalized aggressive periodontitis

Abstract

PurposeAggressive periodontitis, especially in its severe form, was traditionally considered to have an unfavourable prognosis. It required a complex treatment and its stabilization was often achieved by surgical therapy. The aim of this study was to investigate the results of nonsurgical periodontal treatment in severe generalized forms of aggressive periodontitis.MethodsPatients with advanced generalized aggressive periodontitis were included in the study. Probing depth (PD) of pockets ≥7 mm and clinical attachment level (CAL) of sites with attachment loss ≥5 mm were measured at baseline before nonsurgical periodontal treatment, at re-evaluation, and after treatment. The following other parameters were recorded: resolution of inflammation and bone fill. We compared the baseline values with re-evaluation and posttreatment values using the Friedman test. The Wilcoxon test with the Bonferroni correction was used for both re-evaluation and posttreatment values.ResultsSeven patients with 266 periodontal sites were examined. A significant difference was found between values, reported as medians with interquartile ranges, for PD at baseline (7.94 [7.33-8.19] mm) and both re-evaluation (4.33 [3.63-5.08] mm) and posttreatment (3.54 [3.33-4.11] mm) values (P=0.002). A significant difference was also found between values for CAL at baseline (9.02 [7.5-9.2] mm) and both re-evaluation (6.55 [6.30-6.87] mm) and posttreatment (6.45 [5.70-6.61] mm) (P=0.002). Inflammation was resolved and angular bone defects were repaired in all cases.ConclusionsThese therapeutic results suggest that this form of periodontitis could have positive outcomes after nonsurgical periodontal treatment. The reparative potential of tissue affected by severe aggressive periodontitis should encourage clinicians to save apparently hopeless teeth in cases of this form of periodontitis.Graphical Abstract

Aggressive Periodontitis Etiology, Pathophysiology, and Treatment: A Recent Review

“…In all cases, angular bone defects were resolved and inflammation was reduced. 60 Nonsurgical therapy consisting of whole-mouth ultrasonic debridement, scaling, and root planing also decreased JP2 clone presence in African-American patients with localized AgP. Using PCR sequencing, JP2 detection was found to be 75% in diseased sites and in 56.67% in healthy sites.…”

Diagnóstico y tratamiento de la periodontitis agresiva

“…Oral hygiene and patient's motivation should also be evaluated (59) , in addition to tooth mobility, occlusal state and root sensitivity.…”