Outcomes of Mohs Micrographic Surgery at the American Society for Dermatologic Surgery International Traveling Mentorship Program International Mohs Fellowship Recognition Units: A Retrospective Survey of 5889 Cases From South Africa, Romania, and the Netherlands

Plessis, Pieter J. du; Leventer, Mihaela; Krekels, Gertruud A. M.; Wet, Jacob D. de; Laeuchli, Severin

doi:10.1097/dss.0000000000002251

Cited by 6 publications

(10 citation statements)

References 20 publications

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“…The NCCN guidelines for the surgical treatment of BCC recommend that low-risk BCCs less than 2 cm in diameter be excised with a 4 mm clinical margin. MMS is the gold standard treatment for high-risk BCCs as it offers the highest cure rate [ 27 – 29 ]. A study evaluating MMS for BCC treatment in SA echoed international data and showed that MMS offers the highest cure rates with a low recurrence rate (0.1%) [ 29 ].…”

Section: Discussionmentioning

confidence: 99%

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A Profile and Three-Year Follow-Up of Patients with Basal Cell Carcinoma in the Western Cape, South Africa

Gallo

Schneider

Wet

et al. 2022

Journal of Skin Cancer

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Background. Basal cell carcinoma (BCC) is an important malignancy in sub-Saharan Africa. There is a paucity of data regarding BCC in South Africa. Aims. To describe the clinicopathological features of patients presenting with BCC in a cohort of South African patients. Methods. This retrospective descriptive study reviewed the medical records of 149 patients with BCC who attended the dermatology clinic at Tygerberg Academic Hospital from September 2015 to August 2016. Demographic and clinical data of those patients with histologically proven BCC were retrieved from clinical records. The data included the assessment for BCC recurrence after three years (September 2016–August 2019). Results. Of 390 patients, 155 (39.7%) had histologically confirmed BCCs. Complete medical records were available for 149 of these patients, and most were male (55.7%) and white (85.9%) with a median age of 70 years. Most patients had their BCC lesions for 12 months (43.1%) before diagnosis. BCCs were mostly located on the head and neck area (58.1%). In most patients (72.0%), a diagnostic punch biopsy confirmed BCC. Plastic surgeons subsequently excised the BCC lesions in 74.0% of these patients. The most common histological subtype was nodular BCC (74.0%). The National Comprehensive Cancer Network (NCCN) risk of recurrence was approximately evenly distributed between high- (54.1%) and low-risk groups (45.9%). The major high-risk feature was the location (36.6%). Histologically confirmed BCC recurrence occurred in 9 of the 149 patients (3.7%) over three years. Conclusions. BCC represents a high burden of disease in our setting. Compared to existing studies, the BCCs in this study are clinically and histologically similar to international reports.

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Section: Discussionmentioning

confidence: 99%

“…MMS is the gold standard treatment for high-risk BCCs as it offers the highest cure rate [ 27 – 29 ]. A study evaluating MMS for BCC treatment in SA echoed international data and showed that MMS offers the highest cure rates with a low recurrence rate (0.1%) [ 29 ]. MMS is not a treatment option at TAH.…”

Section: Discussionmentioning

confidence: 99%

A Profile and Three-Year Follow-Up of Patients with Basal Cell Carcinoma in the Western Cape, South Africa

Gallo

Schneider

Wet

et al. 2022

Journal of Skin Cancer

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“…In some countries, such as the United States, MMS dermatologists are allowed both to perform the surgical procedure and sign the pathology report. Moreover, the management of post‐operative closures is heterogeneous: in some MMS centers, dermatologists and plastic surgeons cooperate, but in other cases it is the exclusive prerogative of dermatologists 25 …”

Section: Discussionmentioning

confidence: 99%

It's time forMohs: Micrographic surgery for the treatment of high‐risk basal cell carcinomas of the head and neck regions

Dika

Veronesi

Patrizi

et al. 2020

Dermatologic Therapy

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Basal cell carcinoma (BCC) is the most common variety of non‐melanoma skin cancer and its incidence is increasing worldwide. The centrofacial sites (area H) are considered a high‐risk factor for BCC local recurrence. Mohs micrographic surgery (MMS) is a technique that allows intraoperative microscopic control of the surgical margins and is a good treatment option when tissue conservation is required for esthetic or functional reasons or for high‐risk lesions. The present study aimed to evaluate the recurrence rate of head and neck high‐risk BCCs comparing MMS vs conventional surgical excision. Clinical data of patients diagnosed from September 2014 to March 2017, referring to the Dermatology Unit of the Policlinico Sant'Orsola‐Malpighi, University of Bologna, were retrospectively evaluated (285 treated with MMS and 378 treated with traditional surgery). Of the 285 patients treated with MMS, 9 experienced a recurrence (3.1%). Of the 378 patients treated with traditional surgery, 53 relapsed (14%), 13 of whom presented residual tumor on the deep or lateral margins of the main surgical specimen. Our study confirms the trend reported in the literature that MMS represents the best treatment option for high‐risk BCCs arising in the head and neck region or presenting as a recurrence (P < .00001). Many more MMS centers and more trained dermatologists are needed worldwide in order to deal with the increasing number of BCC diagnosed every year.

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“…Since Dr. Mohs’s initial work in the 1930s, the practice of MMS has become increasingly widespread among the dermatologic surgery community worldwide and is now considered the treatment of choice for many common and uncommon cutaneous neoplasms. 11 , 12 , 13 , 14 , 15 …”

Section: Historymentioning

confidence: 99%

Mohs micrographic surgery: a review of indications, technique, outcomes, and considerations

Bittner

Cerci

Kubo³

et al. 2021

Anais Brasileiros de Dermatologia

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Mohs micrographic surgery is a specialized form of skin cancer surgery that has the highest cure rates for several cutaneous malignancies. Certain skin cancers can have small extensions or “roots” that may be missed if an excised tumor is serially cross-sectioned in a “bread-loaf” fashion, commonly performed on excision specimens. The method of Mohs micrographic surgery is unique in that the dermatologist (Mohs surgeon) acts as both surgeon and pathologist, from the preoperative considerations until the reconstruction. Since Dr. Mohs’s initial work in the 1930s, the practice of Mohs micrographic surgery has become increasingly widespread among the dermatologic surgery community worldwide and is considered the treatment of choice for many common and uncommon cutaneous neoplasms. Mohs micrographic surgery spares the maximal amount of normal tissue and is a safe procedure with very few complications, most of them managed by Mohs surgeons in their offices. Mohs micrographic surgery is the standard of care for high risks basal cell carcinomas and cutaneous squamous cell carcinoma and is commonly and increasingly used for melanoma and other rare tumors with superior cure rates. This review better familiarizes the dermatologists with the technique, explains the difference between Mohs micrographic surgery and wide local excision, and discusses its main indications.

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Outcomes of Mohs Micrographic Surgery at the American Society for Dermatologic Surgery International Traveling Mentorship Program International Mohs Fellowship Recognition Units: A Retrospective Survey of 5889 Cases From South Africa, Romania, and the Netherlands

Cited by 6 publications

References 20 publications

A Profile and Three-Year Follow-Up of Patients with Basal Cell Carcinoma in the Western Cape, South Africa

A Profile and Three-Year Follow-Up of Patients with Basal Cell Carcinoma in the Western Cape, South Africa

It's time forMohs: Micrographic surgery for the treatment of high‐risk basal cell carcinomas of the head and neck regions

Mohs micrographic surgery: a review of indications, technique, outcomes, and considerations

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