Outcomes of Middle Eastern patients undergoing percutaneous coronary intervention: The primary analysis of the First Jordanian PCI Registry

Alhaddad, Imad A.; Tabbalat, Ramzi; Khader, Yousef; Al-Mousa, Eyas; Izraiq, Mahmoud; Nammas, Assem; Jarrah, Mohamad; Saleh, Akram; Hammoudeh, Ayman

doi:10.4103/1995-705x.206206

Cited by 12 publications

(14 citation statements)

References 20 publications

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“…The stent delivery success rate (>99%) was high, and the cardiac event rate at 1 year was low with low rates for cardiac death (0.6%), all MIs (0.9%) and an acceptable stent thrombosis rate (1.1%). 15 , 16 The patient population enrolled was a typical – yet unique – daily life population for this referral center with a remarkably high percentage of diabetes mellitus and other cardiovascular risk factors, and a significant number of patients presented with an acute coronary syndrome (unstable angina or an acute or recent MI). 17 …”

Section: Discussionmentioning

confidence: 99%

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Applying DESyne coronary stent system in patients with ischemic heart disease: experience from Jordan

Jarrah

Alrabadi

Alzoubi

2018

MDER

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BackgroundThe safety and efficacy of drug-eluting coronary stenting have been established for various degrees of severity of coronary artery disease. The DESyne is a contemporary cobalt–chromium thin-strut stent which has been studied in low-risk patients so far.AimThe aim of this study was to evaluate the safety, efficacy and performance of the DESyne stent in patients with an indication for coronary stent implantation at the King Abdullah University Hospital (KAUH), Jordan.Patients and methodsHospital records for all patients implanted with DESyne stent were retrospectively reviewed. Specific clinical events were recorded for all cases, and their incidence rates were estimated by the Kaplan–Meier method. A total of 715 patients (79.3% males and 58.3% with diabetes) with a mean age of 57.8±10.3 years were enrolled in this study. An acute coronary syndrome was the most frequent indication for stenting in 86.3% of the patients (unstable angina 72.0%, myocardial infarction [MI] 14.3%). A total of 849 lesions (1.2 lesions/patient) were treated with the DESyne stent.ResultsAfter 1 year of follow-up, the death rates from cardiac or noncardiac causes were 0.6% and 1.1%, respectively. MI was observed in 0.9% of the cases, and an ischemia-driven revascularization was performed in 0.8% of them. The definite/probable stent thrombosis rate was 1.1%.ConclusionFavorable clinical event rates including cardiac death, MI and stent thrombosis were observed for the DESyne stent in ischemic heart patients especially those with high prevalence of diabetes mellitus and acute coronary syndrome.

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Section: Discussionmentioning

confidence: 99%

“…Outcomes of the first Jordanian PCI study have been reported in a separate article. 16 In total, 2,426 patients were enrolled whom underwent a PCI at 12 tertiary-care centers in Jordan. The mean age was 56±11 years, and 79% were male.…”

Section: Discussionmentioning

confidence: 99%

Applying DESyne coronary stent system in patients with ischemic heart disease: experience from Jordan

Jarrah

Alrabadi

Alzoubi

2018

MDER

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“…Patients with acute coronary syndrome (ACS) are identified as those facing complicated health issues [ 5 ]. Studies conducted by Alhaddad et al and Alsheikh-Ali et al indicated ACS as one of the leading causes of death specifically in Middle East [ 6 , 7 ]. Moreover, it has been identified as considerably responsible for the occurrence of increased deaths due to cardiovascular diseases (CVDs) [ 8 , 9 ].…”

Section: Introductionmentioning

confidence: 99%

An observational study of the occurrence of acute coronary syndrome (ACS) among jordanian patients: Identifying the influence of Ramadan Fasting

Raffee

Alawneh

Suleiman

et al. 2020

Annals of Medicine and Surgery

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Introduction Patients with Acute Coronary Syndrome (ACS) tend to face several health issues during the Holy month of Ramadan, due to the change in dietary patterns. This study aims to investigate the influence of fasting during Ramadan on the occurrence of ACS. Methods The study followed a retrospective observational design, and was conducted in King Abdullah University Hospital (KAUH) of Jordan, during the period of June 06, 2016 to Aug 08, 2016 and May 27, 2017 to July 27, 2017. Data was collected from a sample of 226 male and female patients, aged between 20 and 80 years with major diagnosis of acute coronary syndrome. Therefore, this is a case series of ACS patients. Results Findings of the study indicated that, Ramadan fasting is insignificantly related to the occurrence of ACS, since no significant difference was found in the incidence of hypertension (65%), diabetes (51.7%), unstable angina (56.6%) and coronary artery disease (CAD) (57.6%) findings during and after Ramadan respectively. Similar, findings were attained for patients' final diagnosis which had normal Kidney Function Test (KFT) (72.5%), platelets (91.5%), and Ejection Fraction (EF) (64.6%). Also, no significant difference was found between patients’ smoking status (61.0%), hospital stay (89.8%) and discharge rate (96.9%). Conclusion The study concluded that there is an insignificant association of Ramadan fasting on the cardiac patients and occurrence of acute coronary syndrome.

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“…Coronary artery disease (CAD) is the first of ten leading causes of death worldwide including the Middle East region as noted by the World Health Organization (WHO) [ 1 ]. The classical cardiovascular risk factors that contribute to the increase in the morbidity and mortality of CAD include hypertension (HTN), diabetes mellitus (DM), dyslipidemia, and cigarette smoking [ 2 , 3 ]. It is globally agreed that lifestyle modifications and cardiovascular risk factor control would reduce the likelihood of sustaining acute coronary syndrome.…”

Section: Introductionmentioning

confidence: 99%

The Impact of Coexistence of Smoking and Diabetes on the Coronary Artery Severity and Outcomes following Percutaneous Coronary Intervention: Results from the 1^ST Jordanian PCI Registry

Jarrah

Al-Khatib

Khader

et al. 2020

International Journal of Vascular Medicine

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Introduction. Diabetes mellitus (DM) and smoking are highly prevalent among Middle Eastern patients admitted with acute coronary syndrome (ACS) or who undergo percutaneous coronary intervention (PCI). Methods. This study used the analysis of the data from the first Jordanian PCI registry (JoPCR1) to determine the impact of coexistence of smoking and diabetes mellitus on the coronary artery severity and outcome following percutaneous coronary intervention in Middle Eastern patients. Results. Of 2426 patients enrolled, 1300 (53.6%) and 1055 (43.5%) were diabetics and smokers, respectively. The patients’ age was 59.0±10.1 and ranged between 24 and 95 years. Males comprised 79.4% of all patients. The patients were divided into four groups: nondiabetic-nonsmokers (22.2%), diabetic-nonsmokers (34.3%), nondiabetic-smokers (24.2%), and diabetic-smokers (19.2%). Compared with the other three groups, patients in the diabetic-nonsmoker group were older, more likely to be females, and having a higher prevalence of hypertension, dyslipidemia, chronic renal disease, and history of CVD and revascularization. Consequently, the diabetic-nonsmoker patients (but not the diabetic-smokers) had a higher prevalence of multivessel CAD and PCI than the other three groups, highlighting the importance of other risk factors (age, gender, metabolic syndrome, and comorbidities) and not only smoking in predisposing for CAD. Furthermore, those patients had a higher incidence of ACS as an indication for PCI than the stable coronary disease (73% vs 27%) and the highest CRUSADE bleeding risk score (63.9%) among other groups. The in-hospital events including in-stent thrombosis and emergency CABG events did not significantly differ among groups (p=0.5 and 0.22). Heart failure and major bleeding events occurred significantly higher among diabetic-nonsmokers compared to other groups. In-hospital deaths occurred significantly more among diabetic-nonsmokers. Moreover, the one-month and one-year follow-up outcome events (the mortality rate, in-stent thrombosis, readmission for ACS, coronary revascularization, and major bleedings) occurred more frequently in the diabetic-nonsmoker group. However, the difference was statistically significant only for major bleeding incidences. Conclusions. In this analysis of a completed prospective Middle Eastern PCI registry, the majority of the diabetic-nonsmoker (and not the diabetic-smokers) patients (73%) presented with ACS. This group was the highest at risk for in-hospital PCI complications as well as the worst in outcomes after one year of follow-up. Those patients were more likely to be older, female, and have the worst cardiovascular baseline features, highlighting the importance of other risk factors (age, gender, metabolic syndrome, and comorbidities) and not only smoking in predisposing for CAD. Thus, more sufficient education about controlling CVD risk factors should be implemented in the Middle Eastern region.

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Outcomes of Middle Eastern patients undergoing percutaneous coronary intervention: The primary analysis of the First Jordanian PCI Registry

Cited by 12 publications

References 20 publications

Applying DESyne coronary stent system in patients with ischemic heart disease: experience from Jordan

Applying DESyne coronary stent system in patients with ischemic heart disease: experience from Jordan

An observational study of the occurrence of acute coronary syndrome (ACS) among jordanian patients: Identifying the influence of Ramadan Fasting

The Impact of Coexistence of Smoking and Diabetes on the Coronary Artery Severity and Outcomes following Percutaneous Coronary Intervention: Results from the 1^ST Jordanian PCI Registry

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Outcomes of Middle Eastern patients undergoing percutaneous coronary intervention: The primary analysis of the First Jordanian PCI Registry

Cited by 12 publications

References 20 publications

Applying DESyne coronary stent system in patients with ischemic heart disease: experience from Jordan

Applying DESyne coronary stent system in patients with ischemic heart disease: experience from Jordan

An observational study of the occurrence of acute coronary syndrome (ACS) among jordanian patients: Identifying the influence of Ramadan Fasting

The Impact of Coexistence of Smoking and Diabetes on the Coronary Artery Severity and Outcomes following Percutaneous Coronary Intervention: Results from the 1ST Jordanian PCI Registry

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The Impact of Coexistence of Smoking and Diabetes on the Coronary Artery Severity and Outcomes following Percutaneous Coronary Intervention: Results from the 1^ST Jordanian PCI Registry