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2015
DOI: 10.1016/j.fertnstert.2015.05.037
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Outcomes of microdissection testicular sperm extraction in men with nonobstructive azoospermia due to maturation arrest

Abstract: Sperm were successfully identified in up to one half of the men with MA after micro-TESE. Among men with MA, late MA seems to be the best predictor of successful sperm retrieval with micro-TESE.

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Cited by 42 publications
(44 citation statements)
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“…Four testicular histologies are known to cause NOA. Hypospermatogenesis, which is the least severe form of NOA, carries the highest surgical SRR of 73-100% while late maturation arrest has a SRR of 27-86%, early maturation arrest has a SRR of 27-40%, and Sertoli Cell Only syndrome (SCOS), which is the most severe form of infertility, has a SRR of 22.5-41% (3)(4)(5)(6).…”
Section: Predictors Of Sperm Retrieval Rates (Srrs) In the Male Patiementioning
confidence: 99%
“…Four testicular histologies are known to cause NOA. Hypospermatogenesis, which is the least severe form of NOA, carries the highest surgical SRR of 73-100% while late maturation arrest has a SRR of 27-86%, early maturation arrest has a SRR of 27-40%, and Sertoli Cell Only syndrome (SCOS), which is the most severe form of infertility, has a SRR of 22.5-41% (3)(4)(5)(6).…”
Section: Predictors Of Sperm Retrieval Rates (Srrs) In the Male Patiementioning
confidence: 99%
“…Diffuse MA in 100 % van de tubuli heeft een genetische etiologie, maar komt weinig voor. In een studie van Bernie et al onder 211 mannen met NOA bij wie MA werd vastgesteld, werd bij 25 % van de patiënten gegeneraliseerde MA gevonden, bij de overige patiënten histologische mengbeelden [22]. De sperm retrieval rate (SRR) bij heterogeen verspreide MA was 35 % ten opzichte van 57 % bij focale MA.…”
Section: Maturatiearrestunclassified
“…De sperm retrieval rate (SRR) bij heterogeen verspreide MA was 35 % ten opzichte van 57 % bij focale MA. Late MA was gunstiger voor de SRR dan vroege MA [22].…”
Section: Maturatiearrestunclassified
“…Уровень люте-инизирующего гормона (ЛГ), фолликулостимули-рующего гормона (или ингибина Б), объем яичек не имеют отрицательного прогностического зна-чения для результативности microTESE [3]. Более того, наблюдается обратная зависимость: эффек-тивность microTESE выше там, где повышен уро-вень ФСГ, а объем яичек ниже 10,0 мл [9]. Отри-цательный прогноз имеет лишь обнаружение таких генетических отклонений, как полные микроделе-ции в AZFa-или AZFb-локусе Y хромосомы, а так-же при ХХ male синдроме [10].…”
Section: Microsurgical Testicular Sperm Extraction (Microtese) In Patunclassified