Outcomes of Interbody Fusion Cages Used in 1 and 2-levels Anterior Cervical Discectomy and Fusion

Niu, Chi‐Chien; Liao, Jen‐Chung; Chen, Wen-Jer; Chen, Lih-Huei

doi:10.1097/bsd.0b013e3181af3a84

Cited by 167 publications

(149 citation statements)

References 27 publications

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“…The relationship between cage subsidence with loss of intervertebral height and kyphotic deformity, as well as clinical outcome, has been discussed in the literature [3,24,33]. Some authors considered case subsidence did not necessarily mean loss of local and general cervical lordosis.…”

Section: Discussionmentioning

confidence: 99%

“…If the collapse of the anterior part of involved disc space was not greater than that of the posterior part, the local lordosis would be preserved, despite the disc space collapse. Niu et al [24] compared clinical and radiological results between titanium cages and PEEK cages. The results showed the cage subsidence in the titanium group was significantly higher, but there was no significant difference between two groups in loss of cervical lordosis and clinical outcome.…”

Section: Discussionmentioning

confidence: 99%

“…Cabraja et al [6] concluded that there was no difference between titanium and PEEK cages in the treatment singlelevel cervical disc degenerative disorders. However, Niu et al [24] study showed the PEEK implants are superior in maintaining cervical interspace height and achieving radiographic fusion, but the rates of successful clinical outcomes were comparable between two groups in 1 and 2-level ACDF patients.…”

Section: Introductionmentioning

confidence: 97%

“…Recently, two studies compared clinical and radiological results of titanium and PEEK cages, but discrepant results were reported [6,24]. Cabraja et al [6] concluded that there was no difference between titanium and PEEK cages in the treatment singlelevel cervical disc degenerative disorders.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Comparison of titanium and polyetheretherketone (PEEK) cages in the surgical treatment of multilevel cervical spondylotic myelopathy: a prospective, randomized, control study with over 7-year follow-up

et al. 2013

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 97%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Comparison of titanium and polyetheretherketone (PEEK) cages in the surgical treatment of multilevel cervical spondylotic myelopathy: a prospective, randomized, control study with over 7-year follow-up

et al. 2013

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“…Following the long-lasting use of autografts and allografts [2,7,8,12,15,24,36,39], intervertebral cages, without or with additional anterior cervical plates, became the most commonly used intervertebral devices [1,14,25,27,30,39].…”

Section: Introductionmentioning

confidence: 99%

Zero-P: a new zero-profile cage-plate device for single and multilevel ACDF. A single Institution series with four years maximum follow-up and review of the literature on zero-profile devices

et al. 2013

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Purpose To analyze the prospectively collected data in a series of patients treated with single-or multilevel ACDF with a stand-alone, zero-profile device, focusing on clinicoradiological outcome, complications and technical hints, and to review the literature on such new devices. Methods Eighty-five patients harboring symptomatic DDD underwent ACDF with the Zero-P cage-plate: 29 at 1-level and 56 at 2-4 levels (total 162 devices). In the multilevel group, 9 patients received a combination of Zero-P and stand-alone cages (hybrid implants). This study focuses on 32 patients with follow-up ranging from 20 to 48 months. NDI, SF-36 and arm pain VAS scores were registered preoperatively and at follow-up visits. Dysphagia was assessed using the Bazaz score. Imaging included X-rays, CT and MRI, also to assess the presence of vertebral body fractures in multilevel cases. Paired Student t test was used for statistical analysis. Results SF-36 and NDI showed a statistically significant improvement (p \ 0.01) and mean arm pain VAS score decreased from 79 to 41. X-rays and CT demonstrated, respectively, a 94.5 % and a 92 % fusion rate. Three patients complained of moderate and two of mild transient dysphagia (15.5 %). No device-related complications occurred and no fractures, secondary to four screws insertion in one vertebral body (i.e., swiss cheese effect), were detected in multilevel cases. In patients with extensive anterior osteophytes only a ''focal spondylectomy'' was required. Conclusion The Zero-P device is safe and efficient, even in multilevel cases. Dysphagia is minimal, extensive anterior osteophytectomy is unnecessary and technical hints may ease the surgical workflow. This is the largest series, with the longest follow-up, reported.

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Impact of surface roughness and bulk porosity on spinal interbody implants

et al. 2022

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Spinal fusion surgeries are performed to treat a multitude of cervical and lumbar diseases that lead to pain and disability. Spinal interbody fusion involves inserting a cage between the spinal vertebrae, and is often utilized for indirect neurologic decompression, correction of spinal alignment, anterior column stability, and increased fusion rate. The long‐term success of interbody fusion relies on complete osseointegration between the implant surface and vertebral end plates. Titanium (Ti)‐based alloys and polyetheretherketone (PEEK) interbody cages represent the most commonly utilized materials and provide sufficient mechanics and biocompatibility to assist in fusion. However, modification to the surface and bulk characteristics of these materials has been shown to maximize osseointegration and long‐term stability. Specifically, the introduction of intrinsic porosity and surface roughness has been shown to affect spinal interbody mechanics, vascularization, osteoblast attachment, and ingrowth potential. This narrative review synthesizes the mechanical, in vitro, in vivo, and clinical effects on fusion efficacy associated with introduction of porosity in Ti (neat and alloy) and PEEK intervertebral implants.

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Outcomes of Interbody Fusion Cages Used in 1 and 2-levels Anterior Cervical Discectomy and Fusion

Abstract: The PEEK cage is superior to the titanium cage in maintaining cervical interspace height and radiographic fusion after 1 and 2-levels anterior cervical decompression procedures.

Cited by 167 publications

References 27 publications

Comparison of titanium and polyetheretherketone (PEEK) cages in the surgical treatment of multilevel cervical spondylotic myelopathy: a prospective, randomized, control study with over 7-year follow-up

Comparison of titanium and polyetheretherketone (PEEK) cages in the surgical treatment of multilevel cervical spondylotic myelopathy: a prospective, randomized, control study with over 7-year follow-up

Zero-P: a new zero-profile cage-plate device for single and multilevel ACDF. A single Institution series with four years maximum follow-up and review of the literature on zero-profile devices

Impact of surface roughness and bulk porosity on spinal interbody implants

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