Outcomes of HIV-Positive Patients Post Cardiac Transplantation

Liu, G.S.; Wolfson, A.M.; Genyk, P.A.; Vucicevic, D.; Pandya, K.; Fong, Michael W.; Nattiv, J.; Li, J.P.; Kingsford, P.; Banankhah, P.; DePasquale, E.C.; Vaidya, A.S.

doi:10.1016/j.healun.2020.01.1305

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“…[8][9][10] Despite these encouraging data, less than 80 HIV-infected patients went through cardiac transplantation until the end of the year 2019. 14 To the best of our knowledge, there have been only a few case reports regarding VA-ECMO implantation in HIV-infected patients. In one of these cases, ECMO was upgraded to long-term LVAD, and the patient underwent successful HTx later.…”

Section: Discussionmentioning

confidence: 99%

“…Several subsequent studies have highlighted that post‐transplant survival rates among patients with well‐controlled HIV infection and stable chronic heart failure are the same as compared with general patient population 8–10 . Despite these encouraging data, less than 80 HIV‐infected patients went through cardiac transplantation until the end of the year 2019 14 . To the best of our knowledge, there have been only a few case reports regarding VA‐ECMO implantation in HIV‐infected patients.…”

Section: Discussionmentioning

confidence: 99%

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Acute heart transplantation from mechanical circulatory support in a human immunodeficiency virus‐positive patient with fulminant myocarditis

et al. 2021

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Since the establishment of highly active antiretroviral therapy, survival rates have improved among patients with human immunodeficiency virus infection giving them the possibility to become transplant candidates. Recent publications revealed that human immunodeficiency virus-positive heart transplant recipients' survival is similar to non-infected patients. We present the case of a 40-year-old human immunodeficiency virus infected patient, who was hospitalized due to severely decreased left ventricular function with a possible aetiology of acute myocarditis, that has later been confirmed by histological investigation of myocardial biopsy. Due to rapid progression to refractory cardiogenic shock, extracorporeal membrane oxygenation implantation had been initiated, which was upgraded to biventricular assist device later. On the 35th day of upgraded support, the patient underwent heart transplantation uneventfully. Our clinical experience confirms that implementation of temporary mechanical circulatory support and subsequent cardiac transplantation might be successful in human immunodeficiency virus-positive patients even in case of new onset, irreversible acute heart failure.

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