Outcomes of Dialysis Initiated During the Neonatal Period for Treatment of End-Stage Renal Disease: A North American Pediatric Renal Trials and Collaborative Studies Special Analysis

Carey, William A.; Talley, Lynya; Sehring, Sally; Jaskula, Janet M.; Mathias, Robert

doi:10.1542/peds.2006-1754

Cited by 96 publications

(100 citation statements)

References 18 publications

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“…Continuous ambulatory peritoneal dialysis therapy in small children is becoming popular day by day but high mortality rate, frequent infections and poor growth are very common in this group of patients [2][3][4][5][6][7] . CAPD was conceptualized and first used by Popovich and Moncrief in 1976 8 .…”

Section: Discussionmentioning

confidence: 99%

Youngest Child Having Continuous Ambulatory Peritoneal Dialysis in Bangladesh : A Case Report

Hasan

Khan

Maruf-Ul-Quader

et al. 2014

Chatt Maa Shi Hosp Med Coll J

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Section: Discussionmentioning

confidence: 99%

Youngest Child Having Continuous Ambulatory Peritoneal Dialysis in Bangladesh : A Case Report

Hasan

Khan

Maruf-Ul-Quader

et al. 2014

Chatt Maa Shi Hosp Med Coll J

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“…Recent data has demonstrated improvement in outcomes in this age group in terms of survival (Carey et al 2007). This appears due to better clinical management and understanding of the underlying renal pathology.…”

Section: Ckd and Sequelae Beyond The First Year Of Lifementioning

confidence: 99%

Chronic Kidney Disease: A Life Course Health Development Perspective

Brophy

Charlton

Carmody

et al. 2017

Handbook of Life Course Health Development

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Chronic kidney disease (CKD) reflects life events that range from maternal-fetal influences to geriatric exposures. The global direct and indirect costs of CKD are high and include maternal-neonatal hospitalization and treatment, acute kidney injury, dialysis and transplant, missed work, and medications, to name a few. The impact of poor diet, adverse childhood experiences, medication use, and failure to follow consistent public health standards are increasingly appreciated as key influences in the development of CKD. Socioeconomic factors can significantly influence the timing and phenotypic expression in people at risk for developing CKD, although more research is needed to understand these mechanisms. In general, biomedicine has been focused on treating well-established CKD morbidity. This strategy has been short sighted and costly. A more cost-effective approach would focus on early life interventions that hold the potential for mitigating CKD risk and its sequelae. This chapter applies the life course health development principles to review determinants and pathways for CKD evolution and identifies of the gaps in our knowledgebase. We also discuss several research strategies for evaluating the life course health development of CKD.

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“…[4][5][6] A displasia renal é a etiologia de DRCT predominante nesta faixa etária. [7][8][9][10][11] A DP neste grupo é um processo desafiante, continuando o seu início a motivar questões médicas e éticas. 6,7,12, A incidência de complicações da técnica é mais elevada, sendo as peritonites e as infeções associadas ao cateter as mais frequentes.…”

Section: 4unclassified

“…6,7,12, A incidência de complicações da técnica é mais elevada, sendo as peritonites e as infeções associadas ao cateter as mais frequentes. 2,9,11,13,14 A taxa de mortalidade abaixo dos dois anos é até 55 vezes mais elevada que noutras idades pediátricas, embora séries recentemente publicadas revelem uma mudança nesta tendência associada à melhoria nos cuidados. 2,8,11,12 A mortalidade associa-se, mais do que à técnica, à presença de comorbilidades como cardiopatia, hipoplasia pulmonar e perturbações do desenvolvimento psicomotor.…”

Section: 4unclassified

Diálise Peritoneal nos Dois Primeiros Anos de Vida: Experiência de uma Unidade de Nefrologia e Transplantação Renal Pediátrica

Deuchande¹,

Mano

Novais³

et al. 2016

Acta Med Port

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Introduction:Peritoneal dialysis is the dialytic method of choice in chronic end-stage renal disease in children. This study main purpose was to characterize the long-term survival of a pediatric population who began peritoneal dialysis within the first two years of life. Material and Methods: A descriptive and retrospective study was performed in a portuguese nephrology and renal transplantation pediatric unit, between January 1991 and August 2014. End-stage renal disease etiology, mortality, comorbidities and complications of peritoneal dialysis and end-stage renal disease, growth and psychomotor development were evaluated. Results: Twenty children started peritoneal dialysis within the first two years of life. There were six deaths, but no deaths of children with primary chronic kidney disease were registered over the past decade. The 14 living children were characterized; 13 were males. Congenital abnormalities of the kidney and urinary tract were the leading etiology of chronic kidney disease (45%). The average age start of peritoneal dialysis was 6.1 months; six children started before 30 days of life. Peritonitis was the most frequent cause of hospitalization. Ten children were transplanted at an average age of 5.3 years. All of the children who are still in peritoneal dialysis have short stature, but nine of the transplanted have final height within the expected for their mid-parental height target range. Nine (64%) had some type of neurodevelopmental delay. Discussion: Peritoneal dialysis is a technique possible and feasible since birth, as evidenced in the study, as more than half of children successfully started it before 6 months of life. It allows long-term survival until the possibility of renal transplantation despite the associated morbidity, including peritonitis and complications of chronic renal disease. The ten transplanted children improved their growth, recovered from chronic anemia and improved dyslipidemia, compared with the period of dialysis. However, the average waiting time until the renal transplant was 5.3 years higher than other international centers. Conclusion: These data support the use of peritoneal dialysis from birth, but complications and the worst growth reflect the need to develop strategies to optimize care relating to nutrition, growth and development and to reduce pre-transplant time.

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Outcomes of Dialysis Initiated During the Neonatal Period for Treatment of End-Stage Renal Disease: A North American Pediatric Renal Trials and Collaborative Studies Special Analysis

Abstract: Neonates with a presumptive diagnosis of end-stage renal disease may initiate long-term dialysis during the first month of life with outcomes comparable to those of patients who initiate dialysis later in infancy.

Cited by 96 publications

References 18 publications

Youngest Child Having Continuous Ambulatory Peritoneal Dialysis in Bangladesh : A Case Report

Youngest Child Having Continuous Ambulatory Peritoneal Dialysis in Bangladesh : A Case Report

Chronic Kidney Disease: A Life Course Health Development Perspective

Diálise Peritoneal nos Dois Primeiros Anos de Vida: Experiência de uma Unidade de Nefrologia e Transplantação Renal Pediátrica

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