Outcomes of Complex Retinal Detachment Repair Using 1000- vs 5000-Centistoke Silicone Oil

Scott, Ingrid U.; Flynn, Harry W.; Murray, Timothy G.; Smiddy, William E.; Davis, Janet L.; Feuer, William J.

doi:10.1001/archopht.123.4.473

Cited by 112 publications

(97 citation statements)

References 53 publications

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“…Comparing silicone oils with different viscosity, the overall results seem to be comparable with a slight advantage for the 5,000- to 5,900-mPas oil in traumatic retinal detachment cases [9]. On the other hand, there are data showing advantages for the 1,000-mPas oil [10].…”

Section: Pure Silicone Oilsmentioning

confidence: 99%

Long-Lasting Endotamponades in Vitreoretinal Surgery

Wagenfeld

Zeitz²,

Skevas³

et al. 2010

Ophthalmologica

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In modern vitreoretinal surgery, a variety of long-lasting endotamponades is available. These endotamponades differ in physical and chemical properties and their usage is based on certain pathological and surgical considerations. With modern endotamponades the treatment and prognosis for some severe diseases of the posterior segment was improved. Besides these supportive features of new endotamponades, the surgeon has to keep in mind that certain steps, like a complete removal of the vitreous and of any traction, are crucial for the success of an operation and that the most supportive step for the retina is complete endotamponade. This review gives an overview of longlasting endotampoandes in vitreoretinal surgery and of the indications for their usage.

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Section: Pure Silicone Oilsmentioning

confidence: 99%

Long-Lasting Endotamponades in Vitreoretinal Surgery

Wagenfeld

Zeitz²,

Skevas³

et al. 2010

Ophthalmologica

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“…However, there is still no definitive answer by clinical trial comparing different-viscosity silicone oils. Some authors favour 5,000-cSt oil [58], others seem to see advantages in using 1,000-cSt oil [59]. …”

Section: Guidance On the Use Of Long-term Silicone Oil Tamponadementioning

confidence: 99%

Is There a Role for Long-Term Silicone Oil Tamponade for More than Twelve Months in Vitreoretinal Surgery?

Stappler

Morphis²,

Irigoyen³

et al. 2011

Ophthalmologica

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Despite modern and sophisticated vitreoretinal techniques, the authors are convinced that an underreported patient group exists, for whom long-term silicone oil tamponade is unavoidable. We conducted a literature review of the current evidence base in order to provide guidance on the ocular tolerance and side effects of long-term silicone oil, weighing up benefits against complications as well as providing an outlook on future silicone oils with improved physical properties. We advocate the removal of silicone oil in all cases; however, one has to recognise that long-term silicone oil tamponade may have to be considered as a measure of last resort for selected patients. There is a clinical need to develop novel, emulsification-resistant tamponades.

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“…[1][2][3][4][5] Many artificial vitreous substitutes (eg, silicone oil, heavy silicone oil, and hydrogels) are used clinically and in experiments using animals. [6][7][8][9][10][11][12][13][14][15] Among these, silicone oil, introduced by Cibis in 1962, is often injected to an eye suffering from severe retinal or choroidal detachment for an extended time period. Although it has saved many blind patients over the past 50 years, it causes concomitant complications, such as glaucoma, cataracts, corneal degeneration, and emulsification.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of supporting role of a foldable capsular vitreous body with magnetic resonance imaging in the treatment of severe retinal detachment in human eyes

Zhang

Wang

Xie

et al. 2011

Eye

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Purpose To determine the supporting role of a novel foldable capsular vitreous body (FCVB) with magnetic resonance imaging (MRI) in the treatment of severe retinal detachment in human eyes. Methods The study examined nine eyes of nine patients. Among the nine eyes, five had suffered penetrating injuries while four had suffered contusions of the eyeball involving large defects of the retina or choroids. A standard three-port pars plana vitrectomy was performed, FCVB was triple-folded and sent into the vitreous cavity; balanced salt solution (BSS) was injected into the capsule to support the retina. Three cardinal axes of nine eyes were examined using MRI at baseline and at the 3-month follow up. Results MRI revealed that the signal intensity of the FCVB was similar to the normal vitreous body, with low-signal intensity on T1-weighted image and high-signal intensity on T2-weighted image. In three pre-operative silicone oil-or heavy silicone oil-filled eyes, FCVBs were not fully inflated, and eyeball deformation was observed in one eye. Shifts of three cardinal axes of three eyes (horizontal, anteroposterior, and vertical) according to MRI, were À4.33, À4.67, and À2.67 mm. In the remaining six eyes, FCVBs were well distributed in the vitreous cavity and evenly supported the retina; the cardinal axes of the eyes were similar to pre-operation. Shifts of three cardinal axes of six eyes were À0.34, À0.34, and À0.34 mm. In a total of nine eyes, shifts of three cardinal axes were À1.67, À1.77, and À1.11 mm. Statistically significant difference showed only between the horizontal axis of nine eyes pre-operatively and post-operativelyConclusion This study demonstrated the effectiveness of MRI to monitor the supporting role of an FCVB in the treatment of severe retinal detachment in human eyes.

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Outcomes of Complex Retinal Detachment Repair Using 1000- vs 5000-Centistoke Silicone Oil

Cited by 112 publications

References 53 publications

Long-Lasting Endotamponades in Vitreoretinal Surgery

Long-Lasting Endotamponades in Vitreoretinal Surgery

Is There a Role for Long-Term Silicone Oil Tamponade for More than Twelve Months in Vitreoretinal Surgery?

Evaluation of supporting role of a foldable capsular vitreous body with magnetic resonance imaging in the treatment of severe retinal detachment in human eyes

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