Outcomes of Chemical Component Paralysis Using Botulinum Toxin for Incisional Hernia Repairs

Rosin, Danny

doi:10.1007/s00268-013-2220-5

Cited by 2 publications

(2 citation statements)

References 1 publication

(1 reference statement)

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“…[4][5][6] As a result of the challenges of abdominal wall surgeries, studies have demonstrated the use of botulinum toxin A (TBA) injection to aid in the operative preparation of incisional hernias. 7,8 TBA is a neurotoxin that acts selectively on the presynaptic cholinergic nerve terminals, blocking the release of acetylcholine. This action will promote relaxation of the lateral muscles of the abdominal wall (internal oblique, external oblique, and transverse abdominal), facilitating the closure of the aponeurosis, as well as decreasing postoperative pain.…”

Section: Introductionmentioning

confidence: 99%

“…This action will promote relaxation of the lateral muscles of the abdominal wall (internal oblique, external oblique, and transverse abdominal), facilitating the closure of the aponeurosis, as well as decreasing postoperative pain. [8][9][10] The goal of using TBA is to perform an elective incisional hernia preparation, to prevent early recurrence and decrease the risk of abdominal compartment syndrome and some complications such as incarceration, bowel obstruction, and incarceration.…”

Section: Introductionmentioning

confidence: 99%

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Use of botulinum toxin in surgical preparation for complex incisional hernias

Gentile¹,

Lima²,

Costa³

et al. 2022

GHOA

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Abdominal wall defects with incisional hernias after surgery represent a great challenge for surgeons due to their technical complexity for treatment, largely attributed to the retraction of the lateral muscles of the abdominal wall. Reconstruction of the abdominal wall is understood to refunctionalize it with the approximation of the rectus abdominis muscles through its midline. The use of botulinum toxin serotype A (TBA) has shown that its use produces a temporary flaccid paralysis in the abdominal muscles, favoring midline closure, caused by muscle flaccidity and greater complacency caused by the toxin.Abdominal hernias result in increased morbidity due to lung restriction, aerophagia, abdominal pain, constipation, and urinary alterations), with a consequent decrease in quality of life.

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