Outcomes of bariatric surgery in the young: a single-institution experience caring for patients under 21 years old

Serrano, Oscar K.; Zhang, Yang; Kintzer, Emily; Moran-Atkin, Erin; Choi, Jenny; Melvin, W. Scott; Camacho, Diego

doi:10.1007/s00464-016-4849-2

Cited by 21 publications

(9 citation statements)

References 40 publications

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“…Current evidence has not established a reduction in adverse CV events with rigorous control of CV risk factors in adolescents with T2DM. Several studies have reported that typically less than a third of these patients achieve their glycaemic or lipid targets and are less likely to be prescribed lipid lowering treatments, reninangiotensin-system inhibitors or anti-platelet agents than T2DM patients presenting in later life [140][141][142][143] .…”

Section: Pharmacological Approachesmentioning

confidence: 99%

Type 2 diabetes in adolescents and young adults

Lascar

Brown

Pattison

et al. 2018

The Lancet Diabetes & Endocrinology

592

486

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The prevalence of type 2 diabetes in adolescents and young adults is dramatically increasing. Similar to older-onset type 2 diabetes, the major predisposing risk factors are obesity, family history, and sedentary lifestyle. Onset of diabetes at a younger age (defined here as up to age 40 years) is associated with longer disease exposure and increased risk for chronic complications. Young-onset type 2 diabetes also affects more individuals of working age, accentuating the adverse societal effects of the disease. Furthermore, evidence is accumulating that young-onset type 2 diabetes has a more aggressive disease phenotype, leading to premature development of complications, with adverse effects on quality of life and unfavourable effects on long-term outcomes, raising the possibility of a future public health catastrophe. In this Review, we describe the epidemiology and existing knowledge regarding pathophysiology, risk factors, complications, and management of type 2 diabetes in adolescents and young adults.

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Section: Pharmacological Approachesmentioning

confidence: 99%

Type 2 diabetes in adolescents and young adults

Lascar

Brown

Pattison

et al. 2018

The Lancet Diabetes & Endocrinology

592

486

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“…38–40 Moreover, we identified baseline sex and race disparities and lower-than-expected proportion of adolescent bariatric surgery cases in males and minorities. Our study did not demonstrate racial disparities in outcomes, including weight loss and remission of ORCs.…”

Section: Resultsmentioning

confidence: 99%

Health Disparities in Adolescent Bariatric Surgery: Nationwide Outcomes and Utilization

Lopez

Jupiter

Bohanon

et al. 2017

Journal of Adolescent Health

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Purpose Bariatric surgery represents an appropriate treatment for adolescent severe obesity but its utilization remains low in this patient population. We studied the impact of race and sex on preoperative characteristics, outcomes, and utilization of adolescent bariatric surgery. Methods Retrospective analysis (2007-2014) of adolescent bariatric surgery using the Bariatric Outcomes Longitudinal Database, a national database that collects bariatric surgical care data. We assessed the relationships between baseline characteristics and outcomes (weight loss and remission of obesity-related conditions (ORCs)). Using the National Health and Nutrition Examination Survey and US census data, we calculated the ratio of severe obesity and bariatric procedures among races and determined the ratio of ratios to assess for disparities. Results 1,539 adolescents underwent bariatric surgery. Males had higher preoperative BMI (51.8±10.5 vs 47.1±8.7), p<0.001) and higher rates of obstructive sleep apnea (OSA) and dyslipidemia. Blacks had higher preoperative BMI (52.4±10.6 vs 47.3±8.3; 48.7±8.8; 48.2±12.1 kg/m2, Whites, Hispanics, and Others, respectively p<0.001) and higher rates of hypertension, OSA, and asthma. Weight loss and ORCs remission rates did not differ between sexes or races. After accounting for the rate of severe obesity in each racial group. White adolescents underwent bariatric surgery at a higher proportion than Blacks and Hispanics (2.5 and 2.3 times higher, respectively). Conclusions Preoperative characteristics vary according to race and sex. Race and sex do not impact twelve-month weight loss or ORC's remission rates. Minority adolescents undergo bariatric surgery at lower-than-expected rates.

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“…25 Even though there were no randomized studies, a metaanalysis confirmed the effectiveness of SG for weight loss in obese adolescents. 22 Although several studies seemed to show that SG provided results similar to those of RYGB, 10,18,26 others found that weight loss after SG was better than with LAGB. 25,27 Obesity is associated with several comorbidities in adolescents and young adults.…”

Section: Discussionmentioning

confidence: 99%

Laparoscopic Sleeve Gastrectomy for Morbid Obesity in Kuwaiti Adolescents

KhoursheedMousa

Al-BaderIbtisam

Mouzannar

et al. 2019

Bariatric Surgical Practice and Patient Care

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Background: Bariatric surgery has superior therapeutic outcomes compared with other existing treatments. Our aim was to evaluate the safety and efficacy of laparoscopic sleeve gastrectomy (SG) in adolescents with obesity. Methods: From February 2012 until March 2018, all adolescents who underwent SG for obesity were analyzed. Demographics were evaluated. The main outcomes measured were change in weight, body mass index (BMI), percentage excess weight loss (%EWL), complications, and reoperations. Results: Twenty-two adolescents (16/6, F/M) underwent SG. Mean age, preoperative weight, and BMI were 16.4-2.1 years, 125.0-30.2 kg, and 45.1-8.1 kg/m 2 , respectively. The mean duration of operation and hospital stay were 54.7-3.9 min and 2-0 days, respectively. The median follow-up was 9 months. The mean weight loss, BMI loss, and %EWL were 36.4-31.8 kg, 13.8-10.5 kg/m 2 , and 50.9%-27.1%, respectively. One patient developed transient vitamin deficiency due to repeated vomiting. Two patients with type 2 diabetes mellitus had complete remission without medications. Conclusions: SG is effective and safe to treat obesity in adolescents. Further studies are needed to evaluate the long-term effects of SG in adolescents.

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Outcomes of bariatric surgery in the young: a single-institution experience caring for patients under 21 years old

Abstract: LGBP and LSG seem to confer comparable weight loss benefit in patients ≤21 years old with acceptable surgical morbidity.

Cited by 21 publications

References 40 publications

Type 2 diabetes in adolescents and young adults

Type 2 diabetes in adolescents and young adults

Health Disparities in Adolescent Bariatric Surgery: Nationwide Outcomes and Utilization

Laparoscopic Sleeve Gastrectomy for Morbid Obesity in Kuwaiti Adolescents

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