Outcomes in Women Undergoing Electrophysiological Procedures

Biase, Luigi Di; Basile, Eloisa; Al‐Ahmad, Amin

doi:10.15420/aer.2013.2.1.41

Cited by 4 publications

(3 citation statements)

References 67 publications

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“…Gender has also been shown to be a significant predictor of ablation success. 22 However, we did not observe this trend in our study since our sample was predominantly male (77.3%). Furthermore, our study population was relatively young, with a mean age of 62 years.…”

Section: Discussioncontrasting

confidence: 63%

Comprehensive atrial fibrillation burden and symptom reduction post-ablation: insights from DECAAF II

Noujaim,

Assaf,

Lim

et al. 2024

Europace

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Introduction Traditional AF recurrence after catheter ablation is reported as a binary outcome. However, a paradigm shift towards a more granular definition, considering arrhythmic or symptomatic burden, is emerging. Hypothesis We hypothesize that ablation reduces AF burden independently of conventional recurrence status in persistent AF patients, correlating with symptom burden reduction. Methods 98 patients with persistent AF from the DECAAFII trial with pre-ablation follow-up were included. Patients recorded daily single-lead ECG strips, defining AF burden as the proportion of AF days among total submitted ECG days. The primary outcome was atrial arrhythmia recurrence. The Atrial Fibrillation Severity Scale (AFSS) was administered pre-ablation and at 12-months post-ablation. Results At follow-up, 69 patients had atrial arrhythmia recurrence and 29 remained in sinus rhythm. These patients were categorized into a recurrence (n=69) and no-recurrence group (n=29). Both groups had similar baseline characteristics, but recurrence patients were older (p=0.005), had a higher prevalence of hyperlipidemia (p=0.007), and a larger LA volume (p=0.01). There was a reduction in AF burden in the recurrence group when compared to their pre-ablation burden (65% vs. 15%, p<0.0001). Utah Stage 4 fibrosis and diabetes predicted less improvement in AF burden. The symptom severity score at 12 months post-ablation was significantly reduced compared to the pre-ablation score in the recurrence group, and there was a significant correlation between the reduction in symptom severity score and AF burden reduction (R=0.39, p=0.001). Conclusion Catheter ablation reduces AF burden irrespective of arrhythmia recurrence post-procedure. There's a strong correlation between AF burden reduction and symptom improvement post-ablation. Notably, elevated left atrial fibrosis impedes AF burden decrease following catheter ablation.

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Section: Discussioncontrasting

confidence: 63%

Comprehensive atrial fibrillation burden and symptom reduction post-ablation: insights from DECAAF II

Noujaim,

Assaf,

Lim

et al. 2024

Europace

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“…Despite increased prevalence of AF in women, it has been observed that fewer women undergo catheter ablation and timing of ablation after onset may be delayed. It is likely that both social and gender-specific attributes play a role in these trends [ 18 ]. It has been reported that female gender is an independent risk factor for AF recurrence, but other studies show that female gender is protective against recurring AF [ 11 ].…”

Section: Discussionmentioning

confidence: 99%

A Retrospective Cohort Study on Predictors for Rehospitalizations With Recurrence of Atrial Fibrillation Post-Catheter Ablation for Atrial Fibrillation

Shah¹,

Mahler²,

Winkle³

et al. 2021

Cureus

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Atrial fibrillation (AF) is the most common cardiac arrhythmia and is increasing in prevalence due to an aging population. Although medications for rhythm and rate control remain the first-line treatment options for many patients, difficulties can include arrhythmia relapse and drug side effects. Catheter ablation or radiofrequency is an alternative treatment modality that can isolate where ectopic arrhythmic sites originate. Several previous studies have examined post-ablation complications and hospitalization rates for arrhythmia recurrence. However, many of these studies used patient data from before 2015. We examined the following data using recent records: pre-procedural patient characteristics, rates of post-procedural hospitalizations with documented recurrence of AF, and patient risk factors associated with these recurrences.

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“…Finally, no significant differences in the outcomes of ablation for atrial flutter and ventricular arrhythmias have been reported, although females were largely underrepresented in studies on ablation of ventricular arrhythmias. 142…”

Section: The Effect Of Gender On Cied Infection and Lead Extractionmentioning

confidence: 99%

The effects of gender on electrical therapies for the heart: procedural considerations, results and complications

et al. 2017

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Use of cardiac implantable devices and catheter ablation is steadily increasing in Western countries following the positive results of clinical trials. Despite the advances in scientific knowledge, tools development, and techniques improvement we still have some grey area in the field of electrical therapies for the heart. In particular, several reports highlighted differences both in medical behaviour and procedural outcomes between female and male candidates. Women are referred later for catheter ablation of supraventricular arrhythmias, especially atrial fibrillation, leading to suboptimal results. On the opposite females present greater response to cardiac resynchronization, while the benefit of implantable defibrillator in primary prevention seems to be less pronounced. Differences on aetiology, clinical profile, and development of myocardial scarring are the more plausible causes. This review will discuss all these aspects together with gender-related differences in terms of acute/late complications. We will also provide useful hints on plausible mechanisms and practical procedural aspects.

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Outcomes in Women Undergoing Electrophysiological Procedures

Cited by 4 publications

References 67 publications

Comprehensive atrial fibrillation burden and symptom reduction post-ablation: insights from DECAAF II

Comprehensive atrial fibrillation burden and symptom reduction post-ablation: insights from DECAAF II

A Retrospective Cohort Study on Predictors for Rehospitalizations With Recurrence of Atrial Fibrillation Post-Catheter Ablation for Atrial Fibrillation

The effects of gender on electrical therapies for the heart: procedural considerations, results and complications

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