Outcomes in Head and Neck Resections That Require Multiple-Flap Reconstructions

Gao, Rebecca W.; Nuyen, Brian; Divi, Vasu; Sirjani, Davud; Rosenthal, Eben L.

doi:10.1001/jamaoto.2018.0835

Cited by 9 publications

(7 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Despite the huge literature, reconstruction still raises disputes about which surgical reconstructive protocol is the best to restore oral defects [78][79][80][81][82][83]. Similarly, the findings reported by included studies showed widely controversial results.…”

Section: Reconstructionmentioning

confidence: 99%

Health-Related Quality of Life in Oral Cancer Patients: Scoping Review and Critical Appraisal of Investigated Determinants

Cicco

Tartaro

Fasano

et al. 2021

Cancers

View full text Add to dashboard Cite

Background: health-related quality of life (HRQOL) represents a secondary endpoint of medical interventions in oncological patients. Our aim was to highlight potential sources of bias that could be encountered when evaluating HRQOL in oral cancer patients. Methods: this review followed PRISMA-ScR recommendations. Participants: patients treated for oral cancer. Concept: HRQOL assessed by EORTC QLQ-C30 and QLQ-H&N35/QLQ-H&N43. A critical appraisal of included studies was performed to evaluate the accuracy of data stratification with respect to HRQOL determinants. Results: overall, 30 studies met the inclusion criteria, totaling 1833 patients. In total, 8 sociodemographic (SDG) and 15 disease/treatment-specific (DT) HRQOL determinants (independent variables) were identified. The mean number of the independent variables was 6.1 (SD, 4.3)—5.0 (SD, 4.0) DT-related and 1.1 (SD, 1.8) SDG-related variables per article. None of the included papers considered all the identified determinants simultaneously. Conclusions: a substantial lack of evidence regarding HRQOL determinants was demonstrated. This strongly weakens the reliability of the reported findings due to the challenging presence of baseline confounding, selection, and omitted variable biases. The proposed approach recommends the use of further evaluation tools that gather more variables in a single score together with a selection of more homogeneous, reproducible, and comparable cohorts based on the identified baseline confounding.

show abstract

Section: Reconstructionmentioning

confidence: 99%

Health-Related Quality of Life in Oral Cancer Patients: Scoping Review and Critical Appraisal of Investigated Determinants

Cicco

Tartaro

Fasano

et al. 2021

Cancers

View full text Add to dashboard Cite

show abstract

“…Free flap reconstruction requires microvascular‐trained personnel and equipment and has limited use in patients with systemic disease and those without adequate recipient vessels. Free flaps are associated with long operating times, high costs, and lengthy patient recovery 1 . Regional flaps generally require shorter operating times, lower costs, and quicker patient recovery.…”

Section: Figurementioning

confidence: 99%

“…Free flaps are associated with long operating times, high costs, and lengthy patient recovery. 1 Regional flaps generally require shorter operating times, lower costs, and quicker patient recovery. The pedicled pectoralis major flap is a classic pedicled flap for head and neck reconstruction; however, the flap is bulkier than free flap alternatives and often requires additional debulking procedures.…”

mentioning

confidence: 99%

Submental Island Flap versus Free Flap Reconstruction for Complex Head and Neck Defects

Jørgensen

Tabatabaeifar

Toyserkani

et al. 2019

Otolaryngol.--head neck surg.

View full text Add to dashboard Cite

Objective Complex soft tissue reconstruction of the head and neck requires a viable, versatile, and dependable flap. Free flaps, such as the radial forearm and anterolateral thigh flap, have been the mainstay of complex head and neck reconstruction. However, a local pedicled flap, such as the submental island flap (SIF), could be a more effective and less demanding alternative. This systematic review and meta-analysis aim to compare free tissue transfer (FTT) with the SIF for head and neck reconstruction. Data Sources We performed a systematic search in PubMed and EMBASE databases. Meta-analysis was performed on outcomes reported in ≥3 studies. Review Methods Candidate articles were assessed for eligibility by 2 authors. Three authors performed data extraction and methodological quality of the included studies using the Newcastle-Ottawa Quality Assessment Form for Cohort Studies. Results The search strategy resulted in 450 studies, of which 7 were included in the analysis, yielding 155 SIF and 198 FTT cases. Operating time and length of stay were significantly lower for the SIF than for FTT ( P = .05 and P = .0008). There was no significant difference between the groups for complete flap loss, debulking revisions, and oncologic recurrence. Conclusion These results suggest that the SIF reduces length of stay and operating time as compared with FTT in head and neck reconstruction. These findings suggest that the SIF can be considered an alternative reconstructive option to FTT when evaluating intraoral, lateral facial, skull base, and parotidectomy defects, given comparable defect size and tumor biology.

show abstract

“…In their study, Gao et al attempted to better assess the outcomes of patients who require multiple-flap reconstruction (2 free flaps or a free and pedicled flap) by performing a well-crafted systematic review. After appropriate screening and study selection, they critically analyzed 24 articles that comprised 487 patients.…”

mentioning

confidence: 99%

“…Despite these limitations, Gao et al provide a sensible guide to reconstructive surgeons and their patients by distilling the disparate reports as systematically and thoughtfully as possible with the available data. The need and utility to use multiple flaps to achieve the best result still have to be assessed on a case by case basis.…”

mentioning

confidence: 99%

Multiple-Flap Reconstruction of Head and Neck Defects

Futran

2018

JAMA Otolaryngol Head Neck Surg

View full text Add to dashboard Cite

Outcomes in Head and Neck Resections That Require Multiple-Flap Reconstructions

Cited by 9 publications

References 36 publications

Health-Related Quality of Life in Oral Cancer Patients: Scoping Review and Critical Appraisal of Investigated Determinants

Health-Related Quality of Life in Oral Cancer Patients: Scoping Review and Critical Appraisal of Investigated Determinants

Submental Island Flap versus Free Flap Reconstruction for Complex Head and Neck Defects

Multiple-Flap Reconstruction of Head and Neck Defects

Contact Info

Product

Resources

About