The importance of cardiac implantable electronic devices (CIEDs) in the
treatment of cardiac rhythm disturbances, heart failure, and the prevention of
sudden cardiac death is indisputable. However, CIED therapy is associated with
complications, among which infections are particularly unfavourable in terms of
prognosis. The diagnosis and management of CIED infections remain complex, with a
significant impact on mortality and healthcare costs. For these reasons, the risk
factors for CIED infections and methods of their prevention have been assessed in
recent years. This review summarises the current state of knowledge on the
subject. We also outlined the role of alternative methods, such as subcutaneous
defibrillators, leadless pacemakers, and wearable cardioverter defibrillators.