Outcomes following impaction bone grafting for treatment of unstable osteochondritis dissecans

Characteristics Associated With Physical Function Trajectories in Older Adults With Cancer During Chemotherapy

“… Abbreviations: gm/dL, grams per deciliter; kg/m 2 , kilograms per meters squared; SD, standard deviation. a Clinically meaningful symptom cut-point scores: Lee Fatigue Scale score ≥3.2 for morning fatigue, ≥5.6 for evening fatigue, ≤6.2 for morning energy, ≤3.5 for evening energy; 25 General Sleep Disturbance Scale score ≥43; 26 Center for Epidemiological Studies-Depression Scale score ≥16; 27 State Anxiety score ≥32.2; Trait Anxiety score ≥31.8; 30 Attentional Function Index score ≤5. 29 Higher scores for Lee Fatigue Scale, General Sleep Disturbance Scale, Center for Epidemiological Studies-Depression Scale, State Anxiety Scale, and Trait Anxiety Scale indicate higher levels of symptoms. Lower scores on the Attentional Function Index and Lee Energy Scale indicate worse attentional function and lower levels of energy, respectively. …”

Impaction Bone Grafting for Treatment of Unstable Osteochondritis Dissecans (OCD) Lesions

“…18 ACI and osteochondral allografts have been used to address larger lesions with nonsalvageable fragments, although neither procedure has emerged as the gold standard secondary to cost, unknown viability of implanted chondrocytes, limited shelf-life, potential for disease transmission, and multiple or unpredictable surgery dates and delays. 16,[19][20][21][22][23] In 2005, Bartlett et. 12 al described a 2-stage procedure, the MACI sandwich technique, which involved bone grafting the OCD defect with cancellous autograft or allograft and harvesting chondrocytes in the first stage, followed by a second-stage for reimplantation of the autologous chondrocytes.…”

“…12 al described a 2-stage procedure, the MACI sandwich technique, which involved bone grafting the OCD defect with cancellous autograft or allograft and harvesting chondrocytes in the first stage, followed by a second-stage for reimplantation of the autologous chondrocytes. Subsequently, Gallo et al 16 reported favorable results of using only the impaction bone grafting aspect of the procedure and never returning for chondrocyte reimplantation. This approach was adopted, in part, due to the marked symptomatic improvement of patients after the impaction bone grafting alone and their desire to not proceed with the anticipated second stage.…”

“…[13][14][15] Impaction bone grafting is a single-stage, less expensive option that has been shown to have favorable outcomes. 16 Therefore, the purpose of this paper is to describe the technique of impaction bone grafting for treating unstable, large (>200 mm 2 ) OCD lesions.…”

Bioprinting of osteochondral tissues: A perspective on current gaps and future trends

“…There are five clinically available treatment options for osteochondral restoration. These include: 1) osteochondral autograft, 2) osteochondral allograft, 3) impaction bone grafting, 4) Autologous chondrocyte implantation (ACI) "Sandwich Technique", and 5) biphasic scaf folds [16][17][18][19][20][21][22][23][24][25][26] . These techniques, along with their strengths and limitations, are summarized in Table 1.…”