Outcomes following Boerhaave's syndrome

Connelly, CL; Lamb, PJ; Paterson-Brown, Simon

doi:10.1308/003588413x13629960049199

Cited by 24 publications

(20 citation statements)

References 17 publications

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“…Other conditions are related to the development of PM [37] . For example, Boerhaave's syndrome is a rare condition characterized by spontaneous esophageal rupture, caused by forceful emesis against the closed cricopharyngeus muscle [40] . Mortality rates with this condition exceed 90% if left untreated, and have been reported to be around 20% even after appropriate surgical/endoscopic management [40] .…”

Section: Discussionmentioning

confidence: 99%

“…For example, Boerhaave's syndrome is a rare condition characterized by spontaneous esophageal rupture, caused by forceful emesis against the closed cricopharyngeus muscle [40] . Mortality rates with this condition exceed 90% if left untreated, and have been reported to be around 20% even after appropriate surgical/endoscopic management [40] . In these cases, the cause of death is primarily overwhelming sepsis associated with mediastinal and pleural contamination [40] .…”

Section: Discussionmentioning

confidence: 99%

“…Mortality rates with this condition exceed 90% if left untreated, and have been reported to be around 20% even after appropriate surgical/endoscopic management [40] . In these cases, the cause of death is primarily overwhelming sepsis associated with mediastinal and pleural contamination [40] .…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Spontaneous Pneumomediastinum as a Potential Predictor of Mortality in Patients with Idiopathic Pulmonary Fibrosis

Colombi¹,

Ehlers-Tenenbaum²,

Palmowski³

et al. 2016

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control group included 36 IPF patients (28 males; median age: 69 years; VC% at baseline: 57%). In a multivariate Cox regression analysis, PM was a significant predictor of mortality [hazard ratio (HR): 3.0; p = 0.032]. Considering only patients experiencing PM at the time of IPF diagnosis (n = 4), PM was a strongly significant predictor of mortality in multivariate analysis (HR: 6.4; p = 0.007). Conclusions: Spontaneous PM is a rare but serious complication in patients with IPF and may be considered as a potential predictor of mortality.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Spontaneous Pneumomediastinum as a Potential Predictor of Mortality in Patients with Idiopathic Pulmonary Fibrosis

Colombi¹,

Ehlers-Tenenbaum²,

Palmowski³

et al. 2016

Respiration

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“…However, some patients present with atypical symptoms such as shock or respiratory distress, and physical exam findings are often non-specific [3]. Unfortunately, the condition is often misdiagnosed as a perforated peptic ulcer or pancreatitis, which can lead to a delay in receiving appropriate treatment [4]. Further evaluation with a chest X-ray, contrast-enhanced CT scan, or gastrointestinal endoscopy should be performed in any patient suspected to have Boerhaave syndrome.…”

Section: Discussionmentioning

confidence: 99%

Successful Management of Delayed Esophageal Rupture with T-Tube Drainage Using Video-Assisted Thoracoscopic Surgery

Woo

Lee

et al. 2016

Korean J Thorac Cardiovasc Surg

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Spontaneous perforation of the esophagus after forceful vomiting is known as Boerhaave syndrome, a rare and life-threatening condition associated with a high rate of mortality. The management of Boerhaave syndrome is challenging, especially when diagnosed late. Herein, we report the successful management of late-diagnosed Boerhaave syndrome with T-tube drainage in a 55-year-old man. The patient was transferred to our institution 8 days after the onset of symptoms, successfully managed by placing a T-tube, and was discharged on postoperative day 46 without complications.

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“…Boerhaave's syndrome is associated with high mortality and morbidity 1. Prompt diagnosis and assessment with soluble contrast swallow coupled with endoscopy are the established standard.…”

Section: Descriptionmentioning

confidence: 99%