Outcomes following antenatal identification of hydrops fetalis: a single-centre experience from 2001 to 2012

Gilby, Damien; Mee, JB; Kamlin, C. Omar F.; Kornman, Louise; Davis, Peter G; Manley, Brett J.

doi:10.1136/archdischild-2017-313604

Cited by 18 publications

(44 citation statements)

References 36 publications

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“…In the past, many were thought to be idiopathic. Recent literature review shows that a cause can be identified prenatally in 65% of cases and up to 85% postnatally [9]. They are broadly divided as maternal, fetal, placental, and idiopathic causes.…”

Section: Nonimmune Fetal Hydrops (Nifh)mentioning

confidence: 99%

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Hydrops Fetalis

Sekar¹

2019

Complications of Pregnancy

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The abnormal accumulation of fluid in two or more fetal space and in some cases is associated with placental edema and polyhydramnios. This can be seen in all trimesters. It is classified as immune and nonimmune fetal hydrops. Immune hydrops fetalis-rhesus alloimmunization and other blood group antibodies cause hemolytic disease of the newborn. Nonimmune hydrops fetalis can be largely divided as fetal, maternal, placental and idiopathic. Pathophysiology, investigations, treatment and counseling are outlined.

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Section: Nonimmune Fetal Hydrops (Nifh)mentioning

confidence: 99%

“…In a recent review of a 12-year retrospective cohort from a single centre [9], the overall survival from diagnosis was 27% increasing to 55% if born alive.…”

Section: Management Of Nifhmentioning

confidence: 99%

Hydrops Fetalis

Sekar¹

2019

Complications of Pregnancy

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“…The survival rates of the patients who have nonimmune hydrops fetalis (NIHF) range between 10 and 70%. These rates may vary depending on the time of the diagnosis, whether terminated cases are included and whether the infants are born alive (Gilby et al, ). The survival rate in fetuses that have HF varies between 12 and 24% (Heinonen, Ryynanen, & Kirkinen, ), and it is much higher in live neonates (40–50%).…”

Section: Introductionmentioning

confidence: 99%

“…The survival rate in fetuses that have HF varies between 12 and 24% (Heinonen, Ryynanen, & Kirkinen, ), and it is much higher in live neonates (40–50%). Although the most common chromosomal anomalies are detected in HF patients diagnosed in early fetal life, mainly cardiovascular diseases cause the cases that are diagnosed following the second trimester (Gilby et al, ; McCoy, Katz, Gould, & Kuller, ; Sohan et al, ; Wafelman, Pollock, Kreutzer, Richards, & Hutchison, ).…”

Section: Introductionmentioning

confidence: 99%

Clinical characteristics and neonatal outcomes of liveborn newborns with hydrops fetalis treated in a tertiary level neonatal intensive care unit

Emiroğlu

Yılmaz

Keçeci

et al. 2020

Birth Defects Research

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Background: This study was performed for examining the neonatal results and aetiological factors of neonates with hydrops fetalis (HF) and determining the factors affecting mortality. Methods:The medical records of liveborn neonates with HF who were admitted to a tertiary Neonatal Intensive Care Unit (NICU) in Konya, Turkey, between 2013 and 2019 were reviewed retrospectively. The demographic data, prenatal intervention, clinical findings, and results of the patients were recorded.Results: A total of 32.6% of the 46 liveborn HF infants had immune HF (IHF), while 67.4% had nonimmune HF (NIHF); there was prenatal diagnoses in 39 (84.7%) cases. Cordocentesis and blood transfusion (n = 14; 30.4%) were the prenatal diagnosis and treatment interventions with the highest rate. A total of 16 patients (34.7%) received in utero interventional treatment. It was determined that the mean gestational age was not associated with mortality; moreover, birthweight (BW), Apgar score and the need for mechanical ventilation affected mortality. Conclusion: The prognosis changes according to different etiologies of HF. However, despite the developments in neonatal care, mortality is still high in HF infants. K E Y W O R D S etiology, hydrops fetalis, neonatal outcome, newborn, survival

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“…The paper published in our sister journal Fetal & Neonatal by Gilby et al 5 addresses two key questions that all expectant parents faced with this problem would ask: what is the cause of the hydrops and will my baby survive? Diagnosis in NIHF is of paramount importance to accurate counselling.…”

mentioning

confidence: 99%