Outcomes After Vascular Surgery Procedures in Patients with COVID-19 Infection: A National Multicenter Cohort Study (COVID-VAS)

Abstract

Objectives:To analyze the outcome of vascular procedures performed in patients with COVID-19 infection during the 2020 pandemic. Methods: This is a multicenter, prospective observational cohort study. We analyzed data from 75 patients with COVID-19 infection undergoing vascular surgery procedures in 17 hospitals across Spain and Andorra between March and May 2020. The primary end point was 30-day mortality. Clinical Trials registry number NCT04333693. Results: The mean age was 70.9 (45-94) and 58 (77.0%) patients were male. Around 70.7% had postoperative complications, 36.0% of patients experienced respiratory failure, 22.7% acute Funding: The paper and analysis were not funded. Declaration of Competing Interest: Authors have nothing to disclose for this specific article. Acknowledgments: The authors thank Andaru Pharma for their technical support of the study database and investigator coordination.

Performance of prognostic scores in prediction of 30-day postoperative mortality in COVID-19 patients after emergency surgery: A retrospective cohort study

“…[ 1 ] Increased risk of postoperative ARDS and sepsis was observed after vascular surgery in COVID-19 patients with a positive qSOFA score. [ 23 ] We observed that a positive quick SOFA score had a 9 times higher risk of mortality as compared to negative.…”

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“…10,33 It is also lower than the 30 day mortality rate of 37.3% after vascular surgery procedures reported in the COVID-VAS multicentre study from Spain for patients with SARS-CoV-2 infection during the first wave. 9 Notably, there was no change in mortality or post-operative complications after vascular procedures in the Swedish registry. 19 The main strength of this study is the large sample size and the long study period, which included the three waves of the pandemic in the UK.…”

“…4 Changes in the provision of vascular services in response to the pandemic have been documented through surveys of healthcare professionals and institutional reviews. [5][6][7] J o u r n a l P r e -p r o o f 4 Outcomes such as post-operative complications and mortality after vascular interventions during the COVID-19 pandemic have also been explored in the COvid-19 Vascular sERvice (COVER) Tier 2 multicentre study, 8 the COVID-VAS study, 9 as well as other single centre and registry studies. [10][11][12][13] However, most studies had a small sample of patients and focused on the first wave of the pandemic that started in March 2020, and did not extend to late 2020 and 2021.…”

Covid-19-Related Arterial Thrombosis

“…Так, в недавно опубликованном многоцентровом проспективном наблюдательном когортном исследовании San Norberto EM et al (2021), где проанализированы данные о 75 пациентах с инфекцией COVID-19, перенёсших сосудистые операции в 17 больницах Испании и Андорры, было показано, что, несмотря на адекватно проведённые оперативные вмешательства и интенсивную терапию, в 20% случаев понадобились повторные операции, в 17,3% -проведены большие ампутации, а 30 дневная летальность составила 37,3%. При этом авторы отмечают, что, если в первую неделю после операции смертность составила 22,7%, тогда как с 8 по 30 сутки она уменьшилась до 14,7% [48].…”