Outcomes After Liver Transplantation in Patients Achieving a Model for End-Stage Liver Disease Score of 40 or Higher

Alexopoulos, Sophoclis P.; Matsuoka, Lea; Cho, Yong; Thomas, Elizabeth; Sheikh, Mohd Raashid; Stapfer, Maria; Dhanireddy, Kiran; Sher, Linda; Selby, Rick; Genyk, Yuri

doi:10.1097/tp.0b013e3182751ed2

Cited by 26 publications

(29 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…These results may lead us to question liver transplantation in patients with MELD score !36. This point is reflected in other articles with different values ranging from 25 to 40 [15,16], including some of them where a relationship between high MELD score and liver transplant outcomes is not demonstrated [16].…”

Section: Discussionmentioning

confidence: 89%

Mind the Model for End-Stage Liver Disease: Model for End-Stage Liver Disease Score as an Indicator of Hemoderivate Transfusion and Survival in Liver Transplantation

Alonso

Maestro

Gómez

et al. 2015

Transplantation Proceedings

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 89%

Mind the Model for End-Stage Liver Disease: Model for End-Stage Liver Disease Score as an Indicator of Hemoderivate Transfusion and Survival in Liver Transplantation

Alonso

Maestro

Gómez

et al. 2015

Transplantation Proceedings

View full text Add to dashboard Cite

“…Variables such as the Model for End‐Stage Liver Disease (MELD) score, donor/recipient age, recipient body mass index (BMI), and pretransplant diagnosis reportedly allow the prediction of short‐term mortality after liver transplantation . Recently, D‐MELD, the product of the donor age and the preoperative MELD score, has been proposed as a highly accurate tool for predicting outcomes after liver transplantation .…”

mentioning

confidence: 99%

Re-evaluation of the predictive score for 6-month graft survival in living donor liver transplantation in the modern era

et al. 2014

View full text Add to dashboard Cite

The limitations of donor age, graft size, and the Model for End-Stage Liver Disease (MELD) score have not been apparent in living donor liver transplantation (LDLT). Our team developed a formula for predicting graft survival after LDLT; the formula includes the graft weight, donor age, MELD score, and portosystemic shunt status. The aims of this study were to re-evaluate the reliability of our formula and to assess whether our modified treatment strategy has improved 6-month graft survival. Two hundred seventeen patients were allocated into 2 groups: patients with predictive scores 1.30 (n 5 162) and patients with predictive scores < 1.30 (n 5 55). The latter group was also divided into subgroups of patients with scores of 1.15 to 1.30 (n 5 37) and patients with scores < 1.15 (n 5 18). Survival rates for patients with scores < 1.30 were significantly worse than rates for patients with scores 1.30 (P 5 0.006). Survival rates for patients with scores < 1.15 were significantly worse than rates for patients with scores of 1.15 to <1.30 (P < 0.001). A multivariate analysis showed that a predictive score < 1.15 (odds ratio 5 7.87, P 5 0.006) and a body mass index 30 kg/m 2 (odds ratio 5 13.3, P < 0.001) were independent risk factors for 6-month graft mortality. In conclusion, predictive scores reliably predict 6-month graft survival and could allow a widening of the safe ranges for donor ages and graft sizes. Liver Transpl 20:323-332, 2014. V C 2013 AASLD.

show abstract

“…With improvements in surgical technique and immunosuppression, recipients have a much better prognosis and life quality than previous years [21,22]. In all of non-renal solid organ transplant, particularly in LTx, CKD has become a critical problem due to multiple risk factors, including DM and immunosuppression.…”

Section: Discussionmentioning

confidence: 99%

Simultaneous pancreas and kidney transplantation for liver transplant recipients with diabetes and uremia

Tam

Zhang²,

Lin³

et al. 2015

Clinics and Research in Hepatology and Gastroenterology

View full text Add to dashboard Cite

Outcomes After Liver Transplantation in Patients Achieving a Model for End-Stage Liver Disease Score of 40 or Higher

Abstract: Acceptable outcomes are achievable after liver transplantation in patients with MELD scores of 40 or higher but come at high pretransplantation and posttransplantation resource utilization.

Cited by 26 publications

References 14 publications

Mind the Model for End-Stage Liver Disease: Model for End-Stage Liver Disease Score as an Indicator of Hemoderivate Transfusion and Survival in Liver Transplantation

Mind the Model for End-Stage Liver Disease: Model for End-Stage Liver Disease Score as an Indicator of Hemoderivate Transfusion and Survival in Liver Transplantation

Re-evaluation of the predictive score for 6-month graft survival in living donor liver transplantation in the modern era

Simultaneous pancreas and kidney transplantation for liver transplant recipients with diabetes and uremia

Contact Info

Product

Resources

About