Outcomes After Conservative, Endoscopic, and Surgical Treatment of Groove Pancreatitis

Abstract

GP is associated with male gender, smoking, and alcohol consumption. The vast majority of patients presents with abdominal pain and with cystic lesions on imaging. Although surgical treatment seems to be the most effective, both conservative and endoscopic treatment are successful in about half of patients. A stepwise treatment algorithm starting with the least invasive treatment options seems advisable.

Pancreas-preserving duodenal resections as a surgery of choice for the isolated form of cystic dystrophy of the duodenal wall (pure form of groove pancreatitis)

“…табл. 1), а также опыту, накопленному итальянскими и французскими коллегами [4,17], консервативная терапия (включая эндоскопическую) и дренирующие процедуры неэффективны в лечении поражения ткани поджелудочной железы при КДДС, хотя есть несколько сообщений о ближайших положительных результатах [7,17,23,43,44]. По нашему мнению, распространение процесса за пределы ДПК у больных КДДС служит показанием к ПДР или пПДР.…”

Pancreaticoduodenectomy and Outcomes for Groove Pancreatitis

“…According to a recently published review study [32], conservative therapy as well as endoscopic and surgical interventions in patients with GP can be effective. These authors recommend a stepwise management with initial conservative therapy.…”

Paraduodenal Pancreatitis: A Deceptive Abdominal Mass with Unique Histologic Findings

“…Alcohol consumption also enhances cholinergic tone to the glands of the minor papilla causing Brunner gland hyperplasia [5,11]. Case Reports in Surgery postprandial abdominal pain (92%), weight loss (78%), and recurrent vomiting (31%) [2]. These symptoms are exacerbated by duodenal stenosis secondary to mass effect.…”

“…However, for patients with less severe symptoms, a variety of less invasive therapies have been found to be effective. These include lifestyle mod-ification, somatostatin analogues, pancreatic duct stenting, biliary duct stenting, and duodenal dilation [2].…”

“…While pancreaticoduodenectomy is occasionally indicated for the treatment of PP, this surgery is often performed solely for diagnostic purposes. This brings significant risk to patients with symptoms that may be treated by less invasive means [2]. Unfortunately, differentiating PP from pancreatic adenocarcinoma and other gastrointestinal cancers prior to resection is challenging.…”