Outcome of Treatment in Verrucous Carcinoma of Oral Cavity: A Tertiary Rural Hospital Experience

Mohammadi, Kouser; Mohiyuddin, S. M. Azeem; Harshitha, N; Suresh, T N; Prasad, Csbr; Sagayaraj, A; Deo, R. P.; Gopinath, K. S.; Manjunath, G. N.; Babu, Ashwin N.; Krishna, Pradeep; Abhilasha, K.; Brindha, H. S.; Pillai, D Aishwarya Raj; Gupta, Arjun

doi:10.1007/s12070-019-01782-z

Cited by 2 publications

(4 citation statements)

References 10 publications

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“…Few other case reports of VC with lymph node metastasis were also reported. However, on re-evaluation, all cases showed the presence of dysplasia/minimal invasion [8,9].…”

Section: Discussionmentioning

confidence: 91%

A Case of Hybrid Verrucous Carcinoma With Lymph Node Metastasis: A Rare Case Report

Sharma¹,

Dk²,

Vyas³

2020

IJCR

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V errucous carcinoma (VC) was first described by Ackerman in 1948. It forms almost 2-12% of all oral malignancies. By strict definition, VC lacks dysplastic cytological features [1]. Few cases of VC were reported associated with dysplasia/minimal invasion and regarded as "in-between" variety of VC. Since there is not enough literature regarding this entity, their clinical, histopathological, and prognostic behavior are unclear [2]. Here, we report a case of "in-between" variety of VC, along with its clinical, pathological, and management aspects.

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“…Few other case reports of VC with lymph node metastasis were also reported. However, on re-evaluation, all cases showed the presence of dysplasia/minimal invasion [8,9].…”

Section: Discussionmentioning

confidence: 91%

A Case of Hybrid Verrucous Carcinoma With Lymph Node Metastasis: A Rare Case Report

Sharma¹,

Dk²,

Vyas³

2020

IJCR

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“…[ 20 ] Rekha and Angadi reported neck dissection in clinically large and aggressive-sized lesions, but lymphadenopathy was reported due to reactive hyperplasia after secondary infection or reported in very few cases. [ 7 21 ] Sadasivan et al . used criteria for neck dissection if tumour size was >4 cm, but after final histopathological report, all were locoregionally controlled.…”

Section: Discussionmentioning

confidence: 99%

“…[ 8 24 30 ] In addition, the surgeon should be more vigilant if there is any suspicion of field cancerisation or other pre-malignant lesions such as leucoplakia, oral submucous fibrosis or dysplasia in VC patients. [ 7 ]…”

Section: Discussionmentioning

confidence: 99%

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Protocol for Treatment of Oral Verrucous Carcinoma - A Systematic Review and Meta-Analysis

Pal

Maurya

Yadav

et al. 2023

Annals of Maxillofacial Surgery

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Background: The objective of this study is to provide a structured protocol for the treatment of verrucous carcinoma (VC) based on size, bone invasion, recurrence and whether neck dissection is necessary or not. In addition, the study evaluates the probability of a wrong histopathological diagnosis. Data Sources: A search was conducted in the Cochrane Library, PubMed and Google from January 1962 to October 2022 by using MeSH terms and keywords. Studies reporting treatment modalities for VC and different histopathological diagnoses after excision of the lesion were selected except case reports and review articles. Study Eligibility Criteria: Thirteen articles were selected. Six hundred and thirty cases of VC were treated by surgery, surgery + neck dissection, radiotherapy, chemotherapy and combination therapy. Statistical analysis revealed surgical treatment as a preferred option. Despite being enlarged, the lymph node was negative for metastasis. So, in OVC cases neck dissection adds only unnecessary morbidity to patients. Participants and Interventions: Radiotherapy or chemotherapy can be used to downstage the disease. 23.3% of cases reported wrong histopathology diagnosis. Study Appraisal and Synthesis Methods: Patients treated for squamous cell carcinoma (SCC) will only experience unnecessary morbidity unless the correct diagnosis is made between VC and hybrid VC. Irrespective of size VC does not metastasise until there are no foci of SCC. Conclusions: Surgical excision of T1- and T2-sized lesions can be performed under local anaesthetic as a biopsy procedure. T3 or T4 lesion can be resected with a safe margin. If it comes as hybrid VC or VC with close margin (0.5 cm, <0.5 cm), neck dissection and further margin should be excised as a second procedure respectively.

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Outcome of Treatment in Verrucous Carcinoma of Oral Cavity: A Tertiary Rural Hospital Experience

Cited by 2 publications

References 10 publications

A Case of Hybrid Verrucous Carcinoma With Lymph Node Metastasis: A Rare Case Report

A Case of Hybrid Verrucous Carcinoma With Lymph Node Metastasis: A Rare Case Report

Protocol for Treatment of Oral Verrucous Carcinoma - A Systematic Review and Meta-Analysis

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