Outcome of trabeculectomies without adjunctive antimetabolites

Gyasi, Michael E; Amoaku, W.M.K.; Debrah, OA; Awini, EA; Abugri, P

doi:10.4314/gmj.v40i2.35986

Cited by 9 publications

(9 citation statements)

References 18 publications

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“…This result is similar with different studies conducted by different authors at different time with different follow up period and population [18,19]. It is supported by the result reported by study conducted in Ghana which indicated that there was statistically significant difference between the mean pre-op and postop IOP (p=0.001) at the last examination at six months [20].…”

Section: Discussionsupporting

confidence: 90%

The Outcome of Trabeculectomy Surgery among Patients at University of Gondar Tertiary Eye Care and Training Center, Northwest Ethiopia

Anbesse¹,

Ayele²,

Gebresellasie³

2017

J Clin Exp Ophthalmol

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Objective: The aim of this study was to assess outcome of Trabeculectomy surgery in terms of preservation of intraocular pressure, visual acuity and optic nerve head defect among patient undergoing trabeculectomy surgery at university of Gondar tertiary eye care and training center. Methods:Hospital based cross sectional study was conducted from January to February 2017. A total of 69 consecutive 'modern' augmented and non-augmented 'safe-technique' trabeculectomies performed over a 2-year period (2012)(2013)(2014) were assessed. Patients' data from the charts were extracted and analyzed by SPSS version 20. Descriptive statistics were done to summarize the data. Paired samples t-test was performed to compare the correspondent preoperative and postoperative IOP, VA and CDR. P-value<0.05% was considered as statistically significant Results: A total of 69 eyes of 63 patients having post-operative follow up of six months were included in the study. The mean age at the presentation was 59.12 ± 12.64 years. On the last day before surgery, mean snellen VA was 0.28 (± 0.23) and it was changed to 0.24 (± 0.20) p=0.38, mean IOP was 31.87 mmHg (± 10.08) and it was reduced to 18.45 mmHg (± 6.12) p=0.001, mean CDR was 0.84 mm (± 0.13) and was changed to 0.85 mm (± 0.12), p= 0.009 at six months after surgery. Complete success and failure of trabeculectomy was 52 (75.4%) and 8 (11.6%), respectively. Conclusion:Based on IOP, the success rate of trabeculectomy was 75.4%. The mean preoperative VA was dropped by one line at six month after surgery and there was significant reduction of IOP from its base line.

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Section: Discussionsupporting

confidence: 90%

The Outcome of Trabeculectomy Surgery among Patients at University of Gondar Tertiary Eye Care and Training Center, Northwest Ethiopia

Anbesse¹,

Ayele²,

Gebresellasie³

2017

J Clin Exp Ophthalmol

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“…3,4 In addition, previous studies have reported that between 22 and 26 percent of all patients operated for glaucoma at the Bawku Hospital in northeastern Ghana are below the age of 40 years. [6][7][8] However, despite these disturbing figures there is currently no nation-wide program to tackle the disease in the country. The study aims at determining the burden and presentation patterns of primary open angle glaucoma, using hospital-based data to highlight the need to develop nationwide intervention strategies to tackle the disease.…”

Section: Introductionmentioning

confidence: 99%

Presentation patterns of primary open angle glaucomas in North eastern Ghana

Gyasi¹,

Amoako²,

Adjuik³

2011

Ghana Medical Journal

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Nearly a third (70.2%) had CDRs>0.8 while more than half (54.9%) had CDRs measured at unity. Males were twice as many as females (65.5% and 34.5% respectively) but blindness sequelae among the latter was twice as much and this was statistically significant (p=0.0008;chi2 test) Conclusion: late presentation of open angle glaucoma cases is a major problem in this part of Ghana. We recommend a more aggressive approach to tackle the disease and reduce its blindness sequelae.

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“…9 Similarly high success rates have been found in other studies among Black West African populations. 10,11 To the best of our knowledge, no prior study in Ghana has investigated the medical treatment as a sole modality for achieving AGIS target levels for IOP. The baseline IOP value reported in this study of 31.9 mmHg to the 6 th month value of 21.3 mmHg does not appear sufficient for adequate POAG control.…”

Section: Discussionmentioning

confidence: 99%

The effect of medical therapy on IOP control in Ghana

Gyasi¹,

Andrew

Adjuik

et al. 2014

Ghana Medical Journal

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SUMMARYBackground: To investigate IOP control following twelve months of continuous medical therapy in Ghana. Methods: This retrospective case series included 163 glaucoma patients diagnosed at a referral eye center between 1996 and 2006. Information collected included age, gender, IOP at presentation, six months and one year post treatment and types of anti-glaucoma medications prescribed. Optimal IOP control was defined according to results from the Advanced Glaucoma Intervention Study (AGIS), which demonstrated arrest of visual field progression in patients with IOP < 18 mmHg at all visitations: Level 1 (post-treatment IOP ≤ 21 mmHg); Level 2 (≤ 18 mmHg) and level 3 (≤ 16 mmHg). The principal outcome measure was the achievement of IOP <18 mmHg at six months and twelve month visitations. Results: One hundred sixty three patients were analyzed. These included 68 males (41.7%) and 95 females (58.3%). The mean age was 57±16 (median 59 years; range 7 -95 years). There was no significant difference in age (p=0.35) or mean IOP (p=0.08) between genders. The mean pre-treated IOP of 31.9±8.9 mmHg significantly decreased to 21.3±6.6 mmHg at 6 months (p=0.001), with 57.4% of eyes at Level 1 IOP control, 25.3% at Level 2 and 15.4% at Level 3 and decreased further at 12 months to 20.7±6.9 mmHg (p=0.48) with 69.7% of eyes at Level 1, 34.4% at Level 2, and 12.4% at Level 3. Conclusions: Current medical regimen is insufficient to reduce IOP to target levels as defined in the Advanced Glaucoma Intervention Study.

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Outcome of trabeculectomies without adjunctive antimetabolites

Abstract: Trabeculectomy alone was effective in controlling IOPs to less than 22 mmHg in POAG. Lower IOP levels needed to control progressive visual field loss may require the use anti-metabolites.

Cited by 9 publications

References 18 publications

The Outcome of Trabeculectomy Surgery among Patients at University of Gondar Tertiary Eye Care and Training Center, Northwest Ethiopia

The Outcome of Trabeculectomy Surgery among Patients at University of Gondar Tertiary Eye Care and Training Center, Northwest Ethiopia

Presentation patterns of primary open angle glaucomas in North eastern Ghana

The effect of medical therapy on IOP control in Ghana

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