Outcome of Total Pelvic Exenteration for Primary Rectal Cancer

Abstract

Total pelvic exenteration may enable long-term survival in younger patients with stage T3 or T4 primary rectal cancer and little or no lymph node metastasis.

En bloc pancreaticoduodenectomy and right hemicolectomy to treat locally advanced right colon cancer: report of three cases

“…This long-term survival following multivisceral resection may be explained by the fact that 45% of cases of locally advanced colorectal cancer do not present any compromised lymph nodes (N0), as we found in our two cases (11,16) . This hypothesis is favored by the fact that there is a specific subgroup of locally aggressive tumors.…”

“…Multivisceral resection of locally advanced colorectal cancer may generally offer long-term survival. Following R0 multivisceral resection, the mean survival has been found to be around 40 months, while the overall fiveyear survival rate is close to 50% (10,16,19) . Specifically in cases of T4 right colon cancer that undergo extended resection with pancreaticoduodenectomy, the median disease-free period may reach 54 months (14) .…”

“…The overall mortality rate following multivisceral resection of locally advanced colorectal cancer has ranged from 0 to 20.8%. Although such mortality has decreased over recent years, the overall morbidity rate remains high, ranging from 20 to 70% (15)(16)(17)(18)(19) . Multivisceral resection of locally advanced colorectal cancer may generally offer long-term survival.…”

Patient follow-up after total small pelvic exenteration for locally advanced rectal cancer

“…Необходимо отметить, что онкологические результаты ЭМТ, выполненных по поводу реци-дивных опухолей прямой кишки, существенно уступают таковым при первичном РПК. Показатель 5-летней общей выживаемости после ЭМТ по поводу рецидивных опухолей в среднем не превы-шает 20-25% [10], тогда как ЭМТ по поводу первичного местно-распространенного РПК позволяет его увеличить до 30-55% [11].…”

A exenteração pélvica para o câncer de reto: avaliação dos fatores prognósticos de sobrevida em 27 pacientes operados

“…Apresentam freqüências variáveis nas diferentes séries descritas. Estima-se que entre 6 e 10% de todas as neoplasias retais se encontrem no estádio T4 no momento de seu diagnóstico (1)(2)(3). Por outro lado, as recidivas pélvicas após cirurgia potencialmente curativa têm variado de 4 a 50% (4)(5)(6)(7)(8).…”