Outcome of Thrombolytic Therapy in Hypertensives with Acute Myocardial Infarction

Abstract

Introduction: Chronic Systemic Hypertension is one of the established cardiovascular risk factors for the development of atherosclerosis and increased incidence of peripheral vascular disease, chronic renal disease, and Coronary Artery disease. Aim: To study the echocardiographic outcome of thrombolysis in hypertensive patients with AMI within 3 days and after 1 month of AMI and to detect left ventricular hypertrophy in such patients by electrocardiography and echocardiography and its influence on left ventricular systolic function. Material and Methods: This is a prospective study to study the echocardiographic outcome of thrombolysis in the Hypertensive patient with Acute Myocardial infarction within 3 days and after one month and to detect left ventricular hypertrophy in such patient by ECG and Echo and its influence on left ventricular systolic function. Results: Among the 26 cases with LVH diagnosed by Echo, 24 diagnosed having LVH with ECG with the sensitivity of 0.9 to 3. Among 24 cases diagnosed as No LVH by Echo, 21 cases were diagnosed as No LVH by ECG with a specificity of 0.875. Conclusion: Patients with LVH after AMI had lower LVEF when compared to there without LVH. The Ejection fraction was shown to improve after one month irrespective of the presence of LVH. The most common conduction Abnormality in the study population was LBBB; Ventricular Tachycardia was commonly associated with Anterior wall MI with poor LVEF.