2002
DOI: 10.1016/s0022-5347(05)65167-1
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Outcome Of Surgical Treatment Of Isolated Local Recurrence After Radical Nephrectomy For Renal Cell Carcinoma

Abstract: Careful followup after radical nephrectomy for renal cell carcinoma allows the diagnosis of small local recurrences before they become symptomatic in the majority of cases. Although most of these patients will eventually have and die of metastatic disease, an aggressive surgical approach is justified and can result in prolonged survival.

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Cited by 96 publications
(68 citation statements)
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“…22 Other small series have reported encouraging results following the excision of hepatic, adrenal, brain, and pancreatic metastases, [23][24][25][26][27] or of isolated local recurrences in the nephrectomy bed. 28,29 Circumstances where patients can undergo resection of residual disease after response to systemic therapy may indeed become more common with the higher tumor shrinkage rates of novel agents described herein. A reevaluation of the efficacy and safety of metastasectomy in this setting is warranted.…”
Section: Role Of Cytoreductive Nephrectomy In Advanced Diseasementioning
confidence: 99%
“…22 Other small series have reported encouraging results following the excision of hepatic, adrenal, brain, and pancreatic metastases, [23][24][25][26][27] or of isolated local recurrences in the nephrectomy bed. 28,29 Circumstances where patients can undergo resection of residual disease after response to systemic therapy may indeed become more common with the higher tumor shrinkage rates of novel agents described herein. A reevaluation of the efficacy and safety of metastasectomy in this setting is warranted.…”
Section: Role Of Cytoreductive Nephrectomy In Advanced Diseasementioning
confidence: 99%
“…Sin embargo existen series donde la recurrencia local está presente en estadíos niciales (T1-T2) 5,10,11 .…”
Section: Grupos De Riesgounclassified
“…Parece ser que los pacientes que han tenido un mayor intervalo de tiempo entre la nefrectomía y la aparición de la recurrencia son los pacientes que tienen mejor pronóstico y mayor probabilidad de que tras el tratamiento de la recurrencia el paciente viva más 5 . Resumiendo, los pacientes con mayor riesgo de tener recidiva local son los tumores avanzados y los que presentan ganglios positivos siendo la recurrencia local en pacientes con T1-2 N0M0 rara.…”
Section: Intervalo Libre De Enfermedadunclassified
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“…1 Local single recurrence following radical nephrectomy is a rare event and occurs in 0.8 to 3.6% of such cases. 2,3 Because RCC is a rare condition without a standardized treatment and chemotherapy and radiotherapy produce poor results, there is interest in the management of this small select group. In this light, we report a case of solitary RCC recurrence following radical nephrectomy that was treated by excision with a good outcome despite other, subsequent recurrences during the follow-up.…”
Section: Introductionmentioning
confidence: 99%