Outcome of strict implementation of infection prevention control measures during an outbreak of Middle East respiratory syndrome

Bushra, H. E. El; Arbash, Hussain A. Al; Mohammed, Mutaz; Abdullahi, Osman; Abdallah, Mohamed N.; Almayahi, Zayid K.; Assiri, Abdullah M.; BinSaeed, Abdulaziz A.

doi:10.1016/j.ajic.2016.12.020

Cited by 21 publications

(21 citation statements)

References 18 publications

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“…It is known that application of standard infection control results in the termination of MERS-CoV outbreaks. 2,4,15,16 Here, we showed a significant increase in the use of PPE (mainly surgical masks, respirators, alcohol-based hand sanitizer, and soap). There was a significant increase in the utilization of surgical masks and respirators during the study period.…”

Section: Discussionmentioning

confidence: 74%

Infection control influence of Middle East respiratory syndrome coronavirus: A hospital-based analysis

Al‐Tawfiq

Abdrabalnabi

Taher

et al. 2019

American Journal of Infection Control

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Background: Middle East respiratory syndrome coronavirus (MERS-CoV) caused multiple outbreaks. Such outbreaks increase economic and infection control burdens. We studied the infection control influence of MERS-CoV using a hospital-based analysis. Methods: Our hospital had 17 positive and 82 negative cases of MERS-CoV between April 1, 2013, and June 3, 2013. The study evaluated the impact of these cases on the use of gloves, surgical masks, N95 respirators, alcohol-based hand sanitizer, and soap, as well as hand hygiene compliance rates. Results: During the study, the use of personal protective equipment during MERS-CoV compared with the period before MERS-CoV increased dramatically from 2,947.4 to 10,283.9 per 1,000 patient-days (P < .0000001) for surgical masks and from 22 to 232 per 1,000 patient-days (P < .0000001) for N95 masks. The use of alcohol-based hand sanitizer and soap showed a significant increase in utilized amount (P < .0000001). Hand hygiene compliance rates increased from 73% just before the occurrence of the first MERS case to 88% during MERS cases (P = .0001). The monthly added cost was $16,400 for included infection control items. Conclusions: There was a significant increase in the utilization of surgical masks, respirators, soap and alcohol-based hand sanitizers. Such an increase is a challenge and adds cost to the healthcare system.

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Section: Discussionmentioning

confidence: 74%

Infection control influence of Middle East respiratory syndrome coronavirus: A hospital-based analysis

Al‐Tawfiq

Abdrabalnabi

Taher

et al. 2019

American Journal of Infection Control

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“…Evidence shows that proper infection prevention and control (IPC) measures during outbreak management could change the course of the outbreak (11). However, the current IPC behaviors are far from optimal.…”

Section: Introductionmentioning

confidence: 99%

Knowledge and preventive practices towards Covid-19 and associated factors among healthcare workers in selected health facilities of Illu Aba Bor and Buno Bedelle Zones, Southwest Ethiopia

Tsegaye

Shuremu²,

Donacho³

et al. 2020

Preprint

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Background The COVID-19 outbreak has been declared a public health emergency of international concern. As the virus is transmitted through close contact and droplets, frontline HCWs caring for COVID-19 patients are at risk of the infection. This study aimed at assessing knowledge and preventive practices towards Covid-19 among health care providers in selected health facilities of Illu Aba Bor and Buno Bedele zones, Southwest Ethiopia. Methods An institution-based cross-sectional study was conducted from April to May 2020 among 330 health workers in selected health facilities of Illu Aba Bor and Buno-Bedelle Zones, Southwest Ethiopia. Data were collected using a self-administered structured questionnaire. The collected data were entered onto Epidata version 3.1 and exported to SPSS version 23 for analysis. Bivariate and multivariable logistic regression analysis was used to identify independent predictors of preventive practices towards Covid-19. Statistical significance was declared at a p-value of < 0.05. Result Greater part (93.3%) of the respondent demonstrated good knowledge towards COVID-19 and the mean (± SD) knowledge score was 9.0 4 ± 1.06. Nearly two-thirds (64.2%) of the study participants had good infection prevention practices. Being male (AOR = 3.65, 95% CI: (1.96, 6.80)), education level (AOR = 1.82, 95% CI (1.02, 3.22)), profession (AOR = 3.17, 95% CI (1.08, 9.33)), service year ( 5–10 years) (AOR = 2.00 (1.02, 3.92)) and more than 10 years (AOR = 3.14 (1.51, 6.52)), availability of personal protective equipment (AOR = 1.96 (1.06, 3.61)) and Knowledge level (AOR = 2.61 (1.48, 4.62)) were independent predictors of COVID-19 preventive practices. Conclusion The overall level of knowledge of HCWs was good. However, the practice was relatively low. Gender, educational status, profession, year of service, knowledge towards COVID-19, and availability of personal protective equipment were independent predictors of good infection prevention practices. Optimizing the infection prevention and control loop of the health facilities is recommended.

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“…1C). Median age of asymptomatic cases was 34 (IQR, [30][31][32][33][34][35][36][37][38][39][40][41][42][43][44][45][46][47][48], the majority of whom were females (70%, n = 47/67) and had no underlying co-morbid conditions (78%, n = 29/37). The proportion of HCP among asymptomatic infections was high (70%, n = 47/67), and the CFR was null.…”

Section: Resultsmentioning

confidence: 99%

“…Factors leading to healthcare-associated outbreaks include overcrowding in emergency departments, slow triage and isolation of suspected patients and inadequate compliance to infection prevention and control procedures 17,23,34 . However, few studies have described or compared the characteristics of HCA-outbreaks as a whole in terms of their size, epidemiologic factors 34,35 , or the role of interventions to stop transmission 23,36 . Here, we provide the largest comprehensive study of eleven healthcare-associated outbreaks that occurred between 2015 and June 2017.…”

mentioning

confidence: 99%

Comparative Analysis of Eleven Healthcare-Associated Outbreaks of Middle East Respiratory Syndrome Coronavirus (Mers-Cov) from 2015 to 2017

Bernard-Stoecklin

Nikolay

Assiri

et al. 2019

Sci Rep

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Since its emergence in 2012, 2,260 cases and 803 deaths due to Middle East respiratory syndrome coronavirus (MERS-CoV) have been reported to the World Health Organization. Most cases were due to transmission in healthcare settings, sometimes causing large outbreaks. We analyzed epidemiologic and clinical data of laboratory-confirmed MERS-CoV cases from eleven healthcare-associated outbreaks in the Kingdom of Saudi Arabia and the Republic of Korea between 2015–2017. We quantified key epidemiological differences between outbreaks. Twenty-five percent (n = 105/422) of MERS cases who acquired infection in a hospital setting were healthcare personnel. In multivariate analyses, age ≥65 (OR 4.8, 95%CI: 2.6–8.7) and the presence of underlying comorbidities (OR: 2.7, 95% CI: 1.3–5.7) were associated with increased mortality whereas working as healthcare personnel was protective (OR 0.07, 95% CI: 0.01–0.34). At the start of these outbreaks, the reproduction number ranged from 1.0 to 5.7; it dropped below 1 within 2 to 6 weeks. This study provides a comprehensive characterization of MERS HCA-outbreaks. Our results highlight heterogeneities in the epidemiological profile of healthcare-associated outbreaks. The limitations of our study stress the urgent need for standardized data collection for high-threat respiratory pathogens, such as MERS-CoV.

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Outcome of strict implementation of infection prevention control measures during an outbreak of Middle East respiratory syndrome

Abstract: The study demonstrated salient evidence that proper institution of IPC measures during management of an outbreak of MERS could remarkably change the course of the outbreak.

Cited by 21 publications

References 18 publications

Infection control influence of Middle East respiratory syndrome coronavirus: A hospital-based analysis

Infection control influence of Middle East respiratory syndrome coronavirus: A hospital-based analysis

Knowledge and preventive practices towards Covid-19 and associated factors among healthcare workers in selected health facilities of Illu Aba Bor and Buno Bedelle Zones, Southwest Ethiopia

Comparative Analysis of Eleven Healthcare-Associated Outbreaks of Middle East Respiratory Syndrome Coronavirus (Mers-Cov) from 2015 to 2017

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