“…In the same way, the International Urogynecological Association's (IUGA) Grafts Roundtable [37] advises against the use of vaginal meshes to correct POP in the presence of stage I-II, local/systemic pain syndromes, or possible pregnancy; in addition, the use of meshes does not seem to be highly effective in the case of prolapse of the posterior compartment or in women aged below 50 years; conversely, the best results seem to be achieved in women aged above 50 years, with stage II prolapse of the anterior compartment, deficient fascia, chronic increase in intra-abdominal pressure, or both, and in the case of relapses [37]. Finally, possible complications with the use of meshes have been reported either during or after prolapse correction, or intraoperatively, i.e., bleeding; injury involving the bladder, ureter or urethra, nerve or bowel; anesthesia-related complications, and deep venous thrombosis (DVT), with the subsequent risk of pulmonary embolism (PE) [34,36]. Postoperative complications include infections, mesh contraction or erosion through the vagina, chronic pain, recurrent voiding symptoms and sexual dysfunctions [34,43,44].…”