Outcome of reflux therapy on pediatric chronic sinusitis

Bothwell, Marcella; Parsons, David; Talbot, A; Barbero, Giulio J.; Wilder, Barbara

doi:10.1016/s0194-5998(99)70181-6

Cited by 163 publications

(109 citation statements)

References 21 publications

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“…Eighteen excluded publications were case series, studying CRS response to GORD treatment (8)(9)(10)(11)(12)(13)(14) , GORD pathogenesis in CRS (8,12,13,(15)(16)(17)(18)(19) , and epidemiological association between GORD and CRS (20)(21)(22)(23)(24)(25) .…”

Section: Search Resultsmentioning

confidence: 99%

Association of gastro-oesophageal reflux and chronic rhinosinusitis: systematic review and meta-analysis

Leason¹,

Barham²,

Oakley³

et al. 2017

Rhin

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Introduction: Gastro-oesophageal reflux disease (GORD) has been implicated in the development of chronic rhinosinusitis (CRS).The association of GORD with CRS is systematically assessed from the medical literature.Methodology: Embase and MEDLINE were searched using a comprehensive strategy limited to English language and Human subjects. Any study with original data on the experimental, diagnostic, treatment or prognostic association of CRS with GORD was included. Studies without a control group, case reports and review articles were excluded. Results:The search returned 958 records, with an additional 10 found from bibliographic lists; this produced 32 studies. The included studies (n=32) consisted of studies reporting pathogenic factors (n=20), epidemiological association (n=8), prognostic interactions (n=3), and a combination of these outcomes (n=1). Potential pathogenic roles for GORD in CRS were supported; CRS subjects had greater prevalence of intranasal Helicobacter pylori and acid reflux than subjects without CRS. CRS is more prevalent in GORD sufferers than those without GORD. Evidence is conflicting for GORD as a factor in CRS treatment failure. Conclusion:The results support a significant association of GORD with CRS. Physicians should be cognizant of the potential for acid and non-acid reflux as a driving factor in CRS.

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Section: Search Resultsmentioning

confidence: 99%

Association of gastro-oesophageal reflux and chronic rhinosinusitis: systematic review and meta-analysis

Leason¹,

Barham²,

Oakley³

et al. 2017

Rhin

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“…An alternative theory of pathogenesis proposes the existence of a reflex response such as has been described with GER and pulmonary disease. 12 Such an esophagonasal or esophagonasopharyngeal reflex that causes sinonasal mucosa to respond to esophageal irritation has not been demonstrated.…”

Section: Commentmentioning

confidence: 99%

Gastroesophageal Reflux Contributing to Chronic Sinus Disease in Children

Cd¹,

We²,

Ws³

et al. 2000

Arch Otolaryngol Head Neck Surg

181

128

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“…These same theories may also apply to chronic sinusitis. Bothwell et al [33] showed that 75% of children with chronic sinusitis had abnormal pH testing, and in 25/28 children sinus symptoms improved with medical antirefl ux treatment. Similar results have been found in adults [34][35][36] .…”

Section: Additional Head and Neck Manifestations Of Eermentioning

confidence: 99%

Extraesophageal Reflux and Upper Aerodigestive Tract Diseases

Jecker¹,

Orloff

Mann³

2005

ORL

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Reflux disease can cause multiple disorders not only of the esophagus but also of the upper aerodigestive tract. In the last decade, an association between reflux disease and multiple head and neck diseases was described, including those of the larynx and pharynx as well as those of the nose, the sinuses and the middle ear. The present article summarizes these different diseases and possible pathomechanisms are explained. In particular, there is a need to differentiate between the classical gastroesophageal reflux disease (GERD) and the extraesophageal manifestation of the reflux disease, called extraesophageal reflux (EER). Both diseases are characterized by different symptoms and can cause different disorders. To differentiate between GERD and EER, double-probe pH monitoring is mandatory. At last, some aspects of reflux therapy are explained.

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Outcome of reflux therapy on pediatric chronic sinusitis

Abstract: After reflux treatment, the number of children requiring sinus surgery was dramatically reduced. The results of this preliminary pediatric study indicate that gastronasal reflux should be evaluated and treated before sinus surgical intervention.

Cited by 163 publications

References 21 publications

Association of gastro-oesophageal reflux and chronic rhinosinusitis: systematic review and meta-analysis

Association of gastro-oesophageal reflux and chronic rhinosinusitis: systematic review and meta-analysis

Gastroesophageal Reflux Contributing to Chronic Sinus Disease in Children

Extraesophageal Reflux and Upper Aerodigestive Tract Diseases

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