Outcome of patients with normal and decreased heart rate variability coronary artery bypass grafting surgey

Abstract

Introduction and objectives: Previous studies have shown that after coronary artery bypass grafting (CABG), heart rate variability (HRV) becomes decreased. The aim of this study was to evaluate the role of decreased heart rate variability in coronary artery bypass grafting patients. Methods: The study involved 119 consecutive patients who underwent the first CABG operation with sinus rhythm. All subjects underwent assessed with 24-hour Holter recordings 2 days preoperative and 7 days postoperative at Hanoi Heart Hospital from 6/2016 to 8/2018. Major adverse cardiovascular events was defined as cardiac death, recurrent myocardial infarction, stroke, decompensated heart failure and re-hospitalization. The patients were followed up for 6 months. Main results: The incidence of major adverse cardiovascular events was 10.8% followed to 6 months. The incidence of pre and postoperative low HRV varies from 28.6% (preop) to 51.8% (postop 7 days). In which, decreased HRV preoperative predictors of major adverse cardiac events in patients undergoing coronary artery bypass graft surgery: followed up for 3 months: (OR:3,40; 95%CI: 0,97 – 12,11; p>0,05), followed up for 6 months (OR:3,41; 95%CI: 1,05 – 11,05; p<0,05). Conclusions: Preoperative with low HRV was pedict a risk factor for major adverse cardiovascular events.