2000
DOI: 10.1097/00005373-200012000-00016
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Outcome of Patients with Diffuse Axonal Injury: The Significance and Prognostic Value of MRI in the Acute Phase

Abstract: MRI is more sensitive compared with computed tomography in the detection of traumatic brain lesions, especially the nonhemorrhagic DAI. The presence of hemorrhage in DAI-type lesions and the association with traumatic space-occupying lesions is a poor prognostic sign. Isolated nonhemorrhagic DAI-type lesions are not associated with poor clinical outcome.

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Cited by 206 publications
(99 citation statements)
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“…However, there can still be problems at the air/tissue interfaces where signal dropout can occur. Some investigators have suggested that the presence of hemorrhage in DAI/TAI is predictive of poor outcome (21). Recent neuropathological investigations show that microscopic analysis continues to detect more DAI/TAI lesions than radiologic imaging (22).…”
Section: Conventional Mri Techniquesmentioning
confidence: 99%
“…However, there can still be problems at the air/tissue interfaces where signal dropout can occur. Some investigators have suggested that the presence of hemorrhage in DAI/TAI is predictive of poor outcome (21). Recent neuropathological investigations show that microscopic analysis continues to detect more DAI/TAI lesions than radiologic imaging (22).…”
Section: Conventional Mri Techniquesmentioning
confidence: 99%
“…Those reports support the Ommaya-Gennarelli model, in which the depth of brain injury correlates with TBI morbidity and mortality. 10,17 However, other studies published by Paterakis et al 8 and Aguas et al 18 have stated that brain stem injury might not necessarily predict a poor prognosis because of good recovery of some patients with TBI affecting the brain stem.…”
mentioning
confidence: 98%
“…Although CT is the imaging technique of choice for initial evaluation of TBI, 5 MR imaging is more sensitive for the depiction of traumatic lesions in the brain parenchyma, 6,7 particularly in the visualization of posterior fossa structures and nonhemorrhagic lesions. 8,9 The relationship between the presence of brain stem injury and clinical outcome is unclear and has varied significantly. 9 Concerning prognosis, the brain stem is one of the most commonly studied anatomic structures.…”
mentioning
confidence: 99%
“…The presence of haemorrhage in DAI-type lesions and the association with traumatic spaceoccupying lesions is a poor prognostic sign. Isolated non haemorrhagic DAI-type lesions have better prognosis [4]. The prognosis also worsens as the number of lesions increase.…”
Section: Discussionmentioning
confidence: 98%