Outcome of pancreaticoduodenectomy in octogenarians: Single institution's experience and review of the literature

Age does not affect complications and overall survival rate after pancreaticoduodenectomy: Single-center experience and systematic review of literature

“…There may be a selection bias (i.e., all subjects were a selected subset of relatively fit patients in the old group): however, the preoperative characteristics were similar between the two groups. As shown in the recent evidence (33,40), PD is certainly a feasible procedure in selected elderly patients.…”

Impact of frailty on surgical outcomes: The right patient for the right procedure

“…1,2 Furthermore, the literature on complex surgical procedures is replete with series of reports on low mortality in older patients. [2][3][4][5] These reports often espouse optimization of patient selection. Unfortunately, the factors comprising such selection criteria remain poorly defined and subjective.…”

Whipple procedure: patient selection and special considerations

“…4 Although age is a risk factor, current studies suggest that PD is an acceptable option for elderly patients. 5 In a review of outcomes of PD completed on 385 patients, 23 patients who were 80 years or older were assessed from 1998 to 2011. When comparing younger patients versus those .80 years of age, the study demonstrated that complication rate (40% vs 43%), mortality rate (4% vs 0%), and overall median survival for pancreatic cancer patients were not statistically different between the groups.…”

“…When comparing younger patients versus those .80 years of age, the study demonstrated that complication rate (40% vs 43%), mortality rate (4% vs 0%), and overall median survival for pancreatic cancer patients were not statistically different between the groups. 5 Langan et al 6,7 assessed 99 elderly patients from 2005 to 2013 and demonstrated that increased age was associated with increased intensive care unit stay, length of stay, and discharge to a skilled facility for rehabilitation. However, octogenarians had equivalent charges and outcome measure when compared with septuagenarians.…”

“…There are case reports of GIST in pancreas. 5 GISTs of the pancreas can be managed with imatinib only, or surgery only, or enucleation or neoadjuvant therapy followed by surgery, or adjuvant therapy after surgery or debulking surgery in metastatic or advanced disease. For lowrisk GISTs, and after an R0 resection has been completed, patients could be managed with surveillance.…”