Outcome of multidisciplinary treatment in laryngeal cancer: A retrospective study with 10-year follow-up

Abstract

Background:In laryngeal cancer, multidisciplinary treatment improves the patient's quality of life and the possibility of preserving the larynx. Most cases occur in a locally advanced stage. The aim is to present the results according to the stage. Method: A retrospective study which analyzed the clinical stage, type of primary treatment, outcomes, and survival was analyzed. Results: A total of 451 patients were included in the study. The median age was 66 years. The majority of the tumors presented in advanced stage (72%) and the most affected subsite was the glottis (84.5%). In the early stage, the most frequent treatment was radiotherapy as the only treatment modality. In Stages III and IVA, 65% were resectable. In Stage IVB, the management was non-surgical, with control in 26% of the cases. Survival at 10 years was related to the clinical stage: 81.7% for Stage I and 0% for Stages IVB and IVC. Conclusions: Patients with laryngeal cancer should be treated according to the clinical stage, through a multidisciplinary approach. Long-term follow-up showed a worse prognosis for advanced clinical stages.

Multidisciplinary treament of laryngeal cancer

“…There are points of controversy in the treatment of laryngeal cancer, which is evident in the interesting article by Gurrola et al 1 recently posted. The most important thing is to obtain local control and survival standards based on the existing evidence from the various therapeutic associations.…”