Outcome of kidney transplantation in patients with systemic autoimmune diseases

Kliem, Volker; Haubitz, Marion; Ehlerding, G.; Nashan, B.; Schlitt, HJ; Oldhafer, Karl J.; Pichlmayr, R.; Koch, K. M.; Brunkhorst, R.

doi:10.1016/s0041-1345(96)00297-7

Cited by 15 publications

(15 citation statements)

References 10 publications

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“…(3,28,38,68). Graft loss at any time postconception was also similar between the two groups, and comparable to losses reported for other post-pregnancy renal recipients, nonpregnant recipients, and male recipients (66,68).…”

Section: Graft Losssupporting

confidence: 75%

“…There were no differences in recipient mortality in our cohorts (SLE 2.6%, non-SLE 2.0%) or as reported in the literature (4,28,(64)(65)(66).…”

Section: Mortalitysupporting

confidence: 46%

“…In a recent review of US data, there was a steady improvement in both short-and long-term renal graft survival from 1988 to 1996 (63). Other series have reported graft outcomes for SLE renal recipients to be similar to outcomes for recipients with other etiologies (8,27,28,(64)(65)(66). No statistical difference was found in 1-year graft survival for 138 SLE renal recipients and 6667 renal recipients with other diagnoses (14).…”

Section: Graft Lossmentioning

confidence: 99%

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Pregnancy Outcomes in Female Renal Recipients: A Comparison of Systemic Lupus Erythematosus With Other Diagnoses

McGrory¹,

McCloskey²,

DeHoratius

et al. 2003

American Journal of Transplantation

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This study compares pregnancy outcomes in systemic lupus erythematosus (SLE) patients post renal transplant with recipients with other primary diagnoses, utilizing data from the National Transplantation Pregnancy Registry, Philadelphia, PA. Recipients were referred from transplant centers nationwide. A retrospective analysis was performed using data from questionnaires, hospital records and telephone interviews. Outcomes of pregnancies post renal transplant secondary to lupus nephritis (SLE: n Ω 38; 60 pregnancies) were compared with the pregnancy outcomes of renal recipients with other diagnoses (non-SLE: n Ω 247; 374 pregnancies). Drug-treated hypertension during pregnancy was less common in the SLE group than in the non-SLE group (45.0% vs. 62.5%, p Ω 0.015). There were fewer cesarean sections in the SLE group (30.2 vs. 53.2%, p Ω 0.008). There was no primary or gestational diabetes in the SLE group. There were no other statistical differences in maternal conditions or pregnancy outcomes between the SLE and non-SLE groups, or in the incidence of post pregnancy graft loss. Female recipients transplanted for renal failure secondary to lupus nephritis can successfully maintain pregnancy. Outcomes are comparable to renal recipients with other diagnoses. Newborns in both groups were often premature and had low birthweight. Overall childhood health was reported to be good; there were no apparent predominant structural malformations among the children.

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Section: Graft Losssupporting

confidence: 75%

“…There were no differences in recipient mortality in our cohorts (SLE 2.6%, non-SLE 2.0%) or as reported in the literature (4,28,(64)(65)(66).…”

Section: Mortalitysupporting

confidence: 46%

Section: Graft Lossmentioning

confidence: 99%

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Pregnancy Outcomes in Female Renal Recipients: A Comparison of Systemic Lupus Erythematosus With Other Diagnoses

McGrory¹,

McCloskey²,

DeHoratius

et al. 2003

American Journal of Transplantation

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“…As expected, most of our study patients had ADPKD. Medullary cystic disease, for which limited published studies on kidney transplant exist, 16,17,20 was the second most frequent primary renal disease requiring kidney transplant. Although MCD is normally clinically milder and typically appears first in adulthood, 5 the average age of ADPKD patients at our center was higher at the time of transplant, probably because these patients usually reach end-stage renal disease at an advanced age.…”

Section: Discussionmentioning

confidence: 99%

“…1,[8][9][10][11][12] Although numerous studies have evaluated the results of kidney transplant in patients with PKD, most of these have only published the results after kidney transplant in patients with ADPKD. [13][14][15][16][17][18] Furthermore, the results have not considered the origin of the graft. Here, we report our single center experience with kidney transplant, providing the largest available single center case series to include all of the PKD types during the last 37 years with a focus on the source of the graft.…”

Section: Introductionmentioning

confidence: 99%

Untitled

Mehrabi

Golriz

Maier

et al. 2015

Exp Clin Transplant

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27%). In deceased-donor versus living-donor transplant recipients, surgical complications included arterial stenosis (1% vs 0%), venous thrombosis (1% vs 0%), urine leakage (0.5% vs 1.9%), ureteral stenosis (0.5% vs 0%), reflux (0% vs 1.9%), lymphocele (11.7% vs 8.1%), and hernia (5.2% vs 8.1%), with no statistically significant differences shown between the groups. The living-donor group had graft and patient survival rates as high as the deceased-donor group. Conclusions: The low rate of morbidity and excellent survival rates make kidney transplant an excellent option for patients with polycystic kidney disease. Although fear of future appearance of polycystic kidney disease may reduce the rate of related living donors, our study showed that graft and patient survival rates in the living-donor group were as high as in the deceased-donor group.

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S1 guidelines Diagnostics and treatment of ANCA-associated vasculitis

Schirmer

Moosig²

2017

Z Rheumatol

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Outcome of kidney transplantation in patients with systemic autoimmune diseases

Cited by 15 publications

References 10 publications

Pregnancy Outcomes in Female Renal Recipients: A Comparison of Systemic Lupus Erythematosus With Other Diagnoses

Pregnancy Outcomes in Female Renal Recipients: A Comparison of Systemic Lupus Erythematosus With Other Diagnoses

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S1 guidelines Diagnostics and treatment of ANCA-associated vasculitis

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