Outcome of frontal lobe epilepsy surgery in adults

Elsharkawy, Alaa Eldin; Alabbasi, Abdel Hamid; Pannek, H. W.; Schulz, Reinhard; Hoppe, Mathias; Pahs, Gerald; Nayel, Mohamed H.; Issa, Ahmed; Ebner, Alois

doi:10.1016/j.eplepsyres.2008.04.017

Cited by 71 publications

(69 citation statements)

References 34 publications

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“…Extratemporal sources are equally prevalent as temporal sources in pediatric epilepsy surgery and constitute a major challenge in terms of electroclinical correlations and postsurgical outcomes [39][40][41]. In particular, frontal lobe epilepsy studies have reported 12-37% of patients without any scalp EEG spikes at all, and a predominance of widespread unilateral or even bilateral spikes in the remaining cases [42][43][44][45]. Factors contributing to the disparity between scalp EEG spikes and their cortical substrates include the inaccessibility of large parts of the frontal lobe to scalp electrodes, the extent of intralobar and interlobar connections, and the presence of secondary bilateral synchrony.…”

Section: Simultaneous Multiscale Eeg Studiesmentioning

confidence: 99%

Correlation of invasive EEG and scalp EEG

Ramantani

Maillard

Koessler

2016

Seizure

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Ever since the implementation of invasive EEG recordings in the clinical setting, it has been perceived that a considerable proportion of epileptic discharges present at a cortical level are missed by routine scalp EEG recordings. Several in vitro, in vivo, and simulation studies have been performed in the past decades aiming to clarify the interrelations of cortical sources with their scalp and invasive EEG correlates. The amplitude ratio of cortical potentials to their scalp EEG correlates, the extent of the cortical area involved in the discharge, as well as the localization of the cortical source and its geometry have been each independently linked to the recording of the cortical discharge with scalp electrodes. The need to elucidate these interrelations has been particularly imperative in the field of epilepsy surgery with its rapidly growing EEG-based localization technologies. Simultaneous multiscale EEG recordings with scalp, subdural and/or depth electrodes, applied in presurgical epilepsy workup, offer an excellent opportunity to shed some light to this fundamental issue. Whereas past studies have considered predominantly neocortical sources in the context of temporal lobe epilepsy, current investigations have included deep sources, as in mesial temporal epilepsy, as well as extratemporal sources. Novel computational tools may serve to provide surrogates for the shortcomings of EEG recording methodology and facilitate further developments in modern electrophysiology.

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Section: Simultaneous Multiscale Eeg Studiesmentioning

confidence: 99%

Correlation of invasive EEG and scalp EEG

Ramantani

Maillard

Koessler

2016

Seizure

View full text Add to dashboard Cite

show abstract

“…In this article, we have described the chronological changes in seizure outcome in a relatively large group of patients. 7,8 In the present study, 54% of patients were followed up for more than 7 years and the mean follow-up period was 81 months. We reviewed all pathological slides and classified cortical dysplasia as suggested by Palmini et al 9…”

Section: Discussionmentioning

confidence: 99%

“…7,8 However, there were 12 cases of late recurrence, which most commonly occurred in patients with cortical dysplasia. Most seizure recurrence occurred within 2 years after surgery, but individual seizure outcome changed in about 5% of patients up to 5 years after the operation.…”

Section: Seizure Recurrencementioning

confidence: 97%

“…Surgical scar, disinhibition of a secondary epileptogenic lesion, residual lesion with low epileptogenic potential, or a residual primary epileptogenic lesion may underlie seizure recurrence. 7,18,19 Identification of specific causes in individual patients would allow the development of better treatment modalities to correct the cause of recurrence. However, it is not possible to identify the cause of recurrence in every patient.…”

Section: Seizure Recurrencementioning

confidence: 99%

“…1,[3][4][5][6] Although the outcome of epilepsy surgery changes with time, few studies have considered longitudinal changes after FLE surgery. 7,8 We previously published a cross-sectional outcome analysis of FLE surgery that did not address chronological changes. 5 Here, we present the longitudinal/chronological changes in the outcome of FLE surgery and identify prognostic factors for this type of surgery.…”

mentioning

confidence: 99%

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