Outcome of esophageal atresia beyond childhood

Rintala, Risto; Sistonen, Saara J.; Pakarinen, Mikko P.

doi:10.1053/j.sempedsurg.2008.10.010

Cited by 92 publications

(107 citation statements)

References 58 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…There are a plethora of studies reporting these outcomes of infants with OA/TOF, with many concentrating on survival and the long-term medical outcomes, including the prevalence of oesophagitis and late malignancy. 7,9,21 Others document surgical technique 22 and specific types of atresia such as long-gap OA. 23,24 Several studies have examined long-term physical and psychosocial outcomes.…”

Section: Discussionmentioning

confidence: 98%

“…These may have a major impact on growth and nutritional status and may also impact on quality of life. 5,7,9 Faugli et al reported that at a median age of 13 months, early mental health disorders were identified using specific diagnostic criteria in 31% of 39 infants, 27 boys and 12 girls, with OA treated in Norway between 1999 and 2002. 10 Although only a relatively small group, these data may have resulted from parental anxieties.…”

Section: Introductionmentioning

confidence: 98%

“…6 While survival of infants with OA continues to improve, there are recognised long-term morbidities, both physical and psychological. [7][8][9] Infants with OA have long-term ongoing physical and nutritional difficulties that may affect their development. Problems include abnormal oesophageal motility, tracheomalacia and gastro-oesophageal reflux.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Early developmental outcome following surgery for oesophageal atresia

Walker

Halliday

Badawi

et al. 2013

J Paediatrics Child Health

View full text Add to dashboard Cite

This study found a lower than expected developmental score for infants following surgery for OA/TOF in the expressive language subscale compared with the healthy control infants. These findings support concerns over the potential impact of OA/TOF and its effects on development. Further studies, including continuing developmental review to determine whether these differences persist and their functional importance, should be performed.

show abstract

Section: Discussionmentioning

confidence: 98%

Section: Introductionmentioning

confidence: 98%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Early developmental outcome following surgery for oesophageal atresia

Walker

Halliday

Badawi

et al. 2013

J Paediatrics Child Health

View full text Add to dashboard Cite

show abstract

“…Pränatal kann ab der 18 [5,6,7,8,9]. Allerdings mangelt es an Daten hinsichtlich der Vor-und Nachteile bei genereller Anwendung in allen kinderchirurgischen Kliniken (.…”

Section: Diagnostikunclassified

Gastrointestinale Atresien

Dingemann

Ure

2011

Monatsschr Kinderheilkd

View full text Add to dashboard Cite

“…Thoracoscopy enables shorter duration of postoperative-assisted ventilation and less days of sedation use [4], whereas thoracotomy may be associated with detrimental musculoskeletal outcomes like weakness of the latissimus dorsi musculature, winging of the scapulae, and thoracic scoliosis [5,6].…”

mentioning

confidence: 99%

The effects of CO2-insufflation with 5 and 10 mmHg during thoracoscopy on cerebral oxygenation and hemodynamics in piglets: an animal experimental study

et al. 2014

View full text Add to dashboard Cite

Objective To evaluate the effect of CO 2 -insufflation with 5 and 10 mmHg on cerebral oxygenation and hemodynamics in neonates. Background An increasing percentage of surgical interventions in neonates are performed by minimal invasive techniques. Recently, concerns have been raised regarding a decrease of cerebral oxygenation in neonates during thoracoscopy as a result of CO 2 -insufflation. Methods This was an animal experimental study. Piglets were anesthetized, intubated, ventilated, and surgically prepared for CO 2 -insufflation. Insufflation was done with 5 or 10 mmHg CO 2 during 1 h. Arterial saturation (SaO 2 ), heart rate (HR), mean arterial blood pressure (MABP), and cerebral oxygenation (rScO 2 ) were monitored. CFTOE, an estimator of cerebral oxygen extraction ((SaO 2 -rScO 2 )/ SaO 2 )), was calculated. Arterial blood gases were drawn every 15 0 : pre (T0), during (T1-T4) and after CO 2 -insufflation (T5). Results Ten piglets (4 kg) were randomized for 5 (P5) and 10 (P10) mmHg CO 2 -insufflation. Two P10 piglets needed resuscitation after insufflation, none P5. Linear mixed-effect modeling of paCO 2 , pH, and SaO 2 showed that values were dependent on time and time squared (p \ 0.001) but were not different between the 5 and 10 mmHg groups. Analysis demonstrated significant changes over time in heart rate and MABP between the 5 and 10 mmHg groups, with a significant higher heart rate and lower blood pressure in the 10 mmHg group (p \ 0.001). For rScO 2 and cFTOE, no group differences could be demonstrated, but a significant effect of time was found: rScO 2 increased and cFTOE decreased (p \ 0.001). Conclusions Insufflation of CO 2 during thoracoscopy with 10 mmHg caused more severe hemodynamic instability and seems to be related with a decrease of cerebral perfusion as represented by a higher oxygen extraction. CO 2 -insufflation of 5 mmHg for thoracoscopy seems to have no adverse effects on cerebral oxygenation.

show abstract

Outcome of esophageal atresia beyond childhood

Cited by 92 publications

References 58 publications

Early developmental outcome following surgery for oesophageal atresia

Early developmental outcome following surgery for oesophageal atresia

Gastrointestinale Atresien

The effects of CO2-insufflation with 5 and 10 mmHg during thoracoscopy on cerebral oxygenation and hemodynamics in piglets: an animal experimental study

Contact Info

Product

Resources

About