Outcome of Delivery Subsequent to Vacuum ‐ Aspiration Abortion in Nulliparous Women

Meirik, Olav; Bergstöm, Reinhold

doi:10.3109/00016348309154226

Cited by 24 publications

(12 citation statements)

References 18 publications

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“…No association between induced abortion and LBW was confirmed by many other investigators (Meirik et al, 1982;Linn et al, 1983;Meirik et al, 1983;Frank et al, 1985;Mandelson et al, 1992).…”

Section: Discussionsupporting

confidence: 57%

“…A number of investigators have studied the effect of previous induced abortion on LBW in subsequent pregnancies, but with conflicting results. Most of the earlier studies indicated no increased risk of LBW following an induced abortion (Meirik et al, 1982;Linn et al, 1983;Meirik et al, 1983;Frank et al, 1985;Mandelson et al, 1992), but later studies have reported a significantly elevated risk of LBW following a previous induced abortion ( Lekea-Karanika et al, 1994;Okonofua et al, 1994). Since the risk may depend upon hospital routines and the health of women who seek an induced abortion, updated studies are needed.…”

Section: Introductionmentioning

confidence: 95%

See 1 more Smart Citation

Induced abortion and prematurity in a subsequent pregnancy: a study from Shanghai

Che

Zhang²,

Gao³

et al. 2001

Journal of Obstetrics and Gynaecology

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To evaluate the impact of a first trimester induced abortion on the risks of low birth weight (LBW) and preterm birth in a subsequent pregnancy we conducted a pregnancy-based cohort study in Shanghai, China with recruitment from 15 general hospitals (or maternity and infant health institutes) from November 1993 to March 1998. Pregnant women with a history of induced abortion entered the abortion cohort and a reference cohort was established among women without such a history. All the subjects were enrolled before 64 days of gestation and interviewed five times until 42 days after delivery. Only singleton live births were analysed in this study. A total of 2953 pregnant women were enrolled and 2707 gave birth to live singletons. The overall incidence of LBW was 1.7%, 2.0% in the abortion cohort and 1.4% in the reference cohort. After controlling the potential confounders using logistic regression, the adjusted odds ratios were 1.7 (95% CI: 0.8-3.3) for LBW, 2.0 (95% CI: 0.9-4.7) for term LBW and 1.0 (95% CI: 0.6-1.5) for preterm birth, following an induced abortion pregnancy. Birth weight in the abortion cohort was 38.5 g higher than that of the reference cohort after adjustment for calendar year at recruitment, couples' occupation, education, age, infant sex, maternal body mass index at recruitment, contraceptive use and gestation age. Previous first trimester induced abortion did not significantly increase the risk of LBW or preterm birth. The study was performed in a low-risk population and results may not be applicable to other settings.

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“…No association between induced abortion and LBW was confirmed by many other investigators (Meirik et al, 1982;Linn et al, 1983;Meirik et al, 1983;Frank et al, 1985;Mandelson et al, 1992).…”

Section: Discussionsupporting

confidence: 57%

Section: Introductionmentioning

confidence: 95%

Induced abortion and prematurity in a subsequent pregnancy: a study from Shanghai

Che

Zhang²,

Gao³

et al. 2001

Journal of Obstetrics and Gynaecology

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show abstract

“…Scandinavian studies largely overcome these methodological limitations by identifying subjects through cross-linked birth and abortion registries. In one such study the authors [25] matched 670 primiparas with a prior vacuum abortion to 622 primiparas and 626 secundiparas who had had no abortions; they found no significant difference in obstetrical outcomes. In a more recent registry-linked study [26], the frequency of preterm delivery was significantly higher in women with histories of induced or spontaneous abortion only when the interpregnancy interval exceeded 12 months; this study did not control for socioeconomic status or smoking during pregnancy.…”

Section: Comparison Of Labor Induction Versus Dande Abortionmentioning

confidence: 99%

Surgical Complications: Prevention and Management

Lichtenberg

Grimes²

2009

Management of Unintended and Abnormal Pregnancy

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L E A R N I N G P O I N T Sr Surgical abortion is one of the safest procedures in contemporary medical practice. r Prophylactic antibiotics reduce the risk of postabortal infection, although the optimum regimen remains unclear. r Failed attempted abortion occurs more commonly in women with uterine anomalies, such as a bicornuate uterus. r Immediate postoperative tissue inspection confirms successful abortion and excludes the remote possibility of an unsuspected ectopic pregnancy in most cases.

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“…At operation, no perforation of the uterus, no cervix laceration and no bleeding exceeding 300 ml occurred which probably indicates that the induced cervical dilatation and uterine tonus reduces the risks for such complications. Preoperative treatment with vaginal suppositories containing 15-methyl-PGFk methyl ester may reduce the complication rate in subsequent pregnancies, but recent studies (6,14) have failed to demonstrate any adverse effect without such pretreatment.…”

Section: Discussionmentioning

confidence: 99%

Vaginal Administration of 15‐ Methyl ‐PGF_2α‐ Methyl Ester Prior to Vacuum Aspiration

Nilsson

Johnell

Langhoff‐Roos

et al. 1983

Acta Obstet Gynecol Scand

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In order to simplify the operative technique and lower the postoperative complication rate, 354 healthy primigravidae were treated with a vaginal suppository containing 1 mg of 15-methyl-prostaglandin F2 alpha 12 hours prior to vacuum aspiration abortion in the first trimester. The mean cervical diameter found at the operation was 8.5 mm and in 38% of the women no further mechanical dilatation of the cervix was needed. The amount of bleeding during the operation was low (mean 30 ml, max. 300 ml). No perforations of the uterus or cervical lacerations occurred at operation. Side effects of the prostaglandin such as vomiting, diarrhea and lower abdominal pain occurred in 80% of the women and must be regarded as disturbing to the patient and seem to require that the women be hospitalized. The incidence of genital infection following the abortion was found to be 6.2%. In 8.2% of the women, the postoperative bleeding persisted for more than 14 days. It is concluded that if the frequency of side effects can be lowered by using new analogues of prostaglandins, pretreatment with vaginal suppositories may be recommended before vacuum-aspiration at legal abortion in the first trimester.

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Outcome of Delivery Subsequent to Vacuum ‐ Aspiration Abortion in Nulliparous Women

Cited by 24 publications

References 18 publications

Induced abortion and prematurity in a subsequent pregnancy: a study from Shanghai

Induced abortion and prematurity in a subsequent pregnancy: a study from Shanghai

Surgical Complications: Prevention and Management

Vaginal Administration of 15‐ Methyl ‐PGF_2α‐ Methyl Ester Prior to Vacuum Aspiration

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Outcome of Delivery Subsequent to Vacuum ‐ Aspiration Abortion in Nulliparous Women

Cited by 24 publications

References 18 publications

Induced abortion and prematurity in a subsequent pregnancy: a study from Shanghai

Induced abortion and prematurity in a subsequent pregnancy: a study from Shanghai

Surgical Complications: Prevention and Management

Vaginal Administration of 15‐ Methyl ‐PGF2α‐ Methyl Ester Prior to Vacuum Aspiration

Contact Info

Product

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Vaginal Administration of 15‐ Methyl ‐PGF_2α‐ Methyl Ester Prior to Vacuum Aspiration